Results 11 to 20 of about 26 (26)

Comparison of physical fitness between healthy and mild‐to‐moderate asthmatic children with exercise symptoms: A cross‐sectional study

open access: yesPediatric Pulmonology, Volume 56, Issue 8, Page 2512-2521, August 2021., 2021
Abstract Objective Asthma is a chronic disease that may affect physical fitness, although its primary effects on exercise capacity, muscle strength, functionality and lifestyle, in children and adolescents, are still poorly understood. This study aimed to evaluate the differences in cardiorespiratory fitness, muscle strength, lifestyle, lung function ...
Verónica Sanz‐Santiago   +10 more
wiley   +1 more source

Pseudohypoxic pheochromocytomas and paragangliomas dominate in children

open access: yesPediatric Blood &Cancer, Volume 68, Issue 7, July 2021., 2021
Abstract Objective Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors that are associated with cancer predisposition syndromes in up to 80% of affected children. PPGLs can be divided into molecularly defined groups with comparable pathogenesis and biology: (1) pseudohypoxic, (2) kinase signaling, and (3) Wnt‐altered. Methods We
Antje Redlich   +5 more
wiley   +1 more source

Abstracts

open access: yes, 2023
Molecular Oncology, Volume 17, Issue S1, Page 1-597, June 2023.
wiley   +1 more source

Broad‐Spectrum Diffusion Coefficient Measurements via Surface Plasmon Resonance: From Thermodynamics to Protein Conformational Disorders

open access: yesChemPhysChem, Volume 26, Issue 16, August 23, 2025.
Recent advancements in surface plasmon resonance protocols and simulations have enhanced the measurement and prediction of diffusion coefficients (D) for chemical species in microfluidic channels. These developments enable precise determination of D values for molecules ranging from a few angstroms to nanometric aggregates, facilitating detailed ...
Giuseppe Stefano Basile   +4 more
wiley   +1 more source

VDAC1‐Targeted NHK1 Peptide Recovers Mitochondrial Dysfunction Counteracting Amyloid‐β Oligomers Toxicity in Alzheimer's Disease

open access: yesAging Cell, Volume 24, Issue 7, July 2025.
Amyloid‐β (Aβ) oligomers affect VDAC1 electrophysiology and the physiological metabolic cross‐talk between cytosol and mitochondria. The use of a small, synthetic VDAC1‐antagonist peptide, derived from hexokinase, restores mitochondrial functionality, and respiration in cellular models of Alzheimer's disease. ABSTRACT Mitochondrial dysfunction has been
Fabrizio Cavallaro   +10 more
wiley   +1 more source

ISEV2022 Abstract Book

open access: yes, 2022
Journal of Extracellular Vesicles, Volume 11, Issue S1, May 2022.
wiley   +1 more source

Valproate discontinuation in girls and women of childbearing age with epilepsy: An Italian multicenter retrospective study on prescribing patterns and outcomes

open access: yesEpilepsia, Volume 66, Issue 5, Page 1529-1539, May 2025.
Abstract Objective This study aimed to identify prescribing behaviors in women of childbearing potential (WOCP) with epilepsy already taking valproate (VPA), and to investigate the relationship between VPA maintenance, substitution, reduction, or withdrawal as part of polytherapy, and seizure worsening or relapse.
Roberta Esposto   +16 more
wiley   +1 more source

Albumin Folding Changes Affect the Microfluidic Interfacial Broadening Revealed by Surface Plasmon Resonance

open access: yesChemistry–Methods, Volume 5, Issue 3, March 2025.
The manuscript introduces a new methodology using Surface Plasmon Resonance (SPR) coupled with stochastic simulations. It reveals albumin′s conformational changes by tracking its diffusion coefficient (D). This approach monitors albumin′s structure in real time under various conditions, including enzymatic cleavage. The findings offer new insights into
Damiano Calcagno   +6 more
wiley   +1 more source

Abstracts

open access: yes, 2021
Research and Practice in Thrombosis and Haemostasis, Volume 5, Issue S2, October 2021.
wiley   +1 more source

Surface Plasmon Resonance Allows to Correlate Molecular Properties With Diffusion Coefficients of Linear Chain Alcohols

open access: yesChemistry – A European Journal, Volume 30, Issue 56, October 8, 2024.
This study introduces a new model to describe and fit the behavior of diffusion coefficients (D) as a function of molecular structure and thermodynamic parameters in binary solutions of linear chain organic molecules. The model is validated using surface plasmon resonance (SPR) experiments and molecular dynamics (MD) simulations for a series of n ...
Giuseppe Stefano Basile   +7 more
wiley   +1 more source

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