Results 1 to 10 of about 70,790 (271)
Ischemia-reperfusion of cardiac tissues may lead to a prominent damage of the cardiomyocyte through either necrosis or apoptosis that seems to be the predominant modes of death during this period. In this study, we investigated the effects of Etanercept
Najah R. Hadi +3 more
doaj +3 more sources
Five-Year Experience of Etanercept as Adjunct to Intravenous Immunoglobulin for Kawasaki Disease with Coronary Artery Involvement [PDF]
Objective: The Etanercept as Adjunctive Treatment for Acute Kawasaki Disease trial was a phase 3, placebo-controlled, randomized trial that evaluated etanercept use for acute Kawasaki disease (KD).
Ryan Rogers, MD +3 more
doaj +2 more sources
Etanercept is a recombinant human receptor fusion protein that suppresses, as a contestant, the interaction of TNF-α with cell surface receptors. It received FDA approval in 1999 to be used in children older than 2 years for the treatment of juvenile ...
Sibel Alper
doaj +2 more sources
Objectives We examined patient-reported outcomes (PROs) in The Study of Etanercept And Methotrexate in Patients with Psoriatic Arthritis (PsA); a 48-week, phase 3, randomised controlled trial that compared outcomes with methotrexate (MTX) monotherapy ...
Vibeke Strand +5 more
doaj +1 more source
Etanercept Ameliorates Cardiac Fibrosis in Rats with Diet-Induced Obesity
Diet-induced obesity (DIO) is considered the main risk factor for cardiovascular diseases. Increases in the plasma levels of tumor necrosis factor alpha (TNF-α) is associated with DIO.
Chia-Chen Hsu +6 more
doaj +1 more source
Adherence to etanercept therapy in rheumatoid arthritis patients during 3 years of follow-up. [PDF]
OBJECTIVES:To determine the percentage non-adherence to etanercept in patients with rheumatoid arthritis during three years of follow-up. METHODS:During study visits in this prospective cohort study, blood samples were taken to determine serum etanercept
E H Vogelzang +7 more
doaj +1 more source
Effect of etanercept on post-traumatic proliferative vitreoretinopathy [PDF]
AIM: To evaluate the safety and efficacy of intravitreal etanercept in the inhibiting of proliferative vitreoretinopathy (PVR) in a model of penetrating ocular injury.
Xiao-Feng Chen +3 more
doaj +1 more source
Etanercept was the first tumour necrosis factor alpha antagonist approved in the USA for the treatment of rheumatoid arthritis, in 1998, and then for other diseases. With the etanercept patent set to expire in the EU in 2015, a number of etanercept copies have reached the production phase and are undergoing clinical trials, with the promise of being ...
Azevedo, Valderilio F. +4 more
openaire +2 more sources
Maternal and Fetal-Placental Effects of Etanercept Treatment During Rats’ Pregnancy
Etanercept is a tumor necrosis factor alpha (TNF-α) inhibitor chronically used to treat autoimmune diseases. However, the use of etanercept during pregnancy still needs to be further investigated.
Gabriel Gomes Araujo +7 more
doaj +1 more source
Etanercept attenuates myocardial ischemia/reperfusion injury by decreasing inflammation and oxidative stress. [PDF]
The protective role of etanercept in myocardial ischemia/reperfusion is not well understood. The aim of this study was to investigate whether etanercept modulates neutrophil accumulation, TNF-α induction and oxidative stress in an ischemia/reperfusion ...
Mei Yang +3 more
doaj +1 more source

