Results 41 to 50 of about 76,618 (225)

A case of postoperative nasopharyngeal reflux associated with retropharyngeal lymphangioma in newborn infant [PDF]

open access: yesKorean Journal of Pediatrics, 2010
Tumor necrosis factor-?#6184;TNF-?#6752;is a major proinflammatory cytokine involved in the pathophysiology of juvenile rheumatoid arthritis. Etanercept is an effective inhibitor of TNF-?#6177;nd has shown a beneficial effect in patients with JRA ...
Ah Reum Kwon   +3 more
doaj   +1 more source

Clinical remission in juvenile idiopathic arthritis after termination of etanercept [PDF]

open access: yes, 2012
Biologicals are very effective for inhibiting disease progression in active juvenile idiopathic arthritis (JIA). To date, there have been no recommendations on how and when to stop therapy with TNF inhibitors. Our objective was to analyze characteristics
Edyta Olesińska   +4 more
core   +1 more source

TNF-α antagonist attenuates systemic lipopolysaccharide-induced brain white matter injury in neonatal rats

open access: yesBMC Neuroscience, 2019
Background Systemic inflammation is an important risk factor for neurodevelopmental impairments in preterm infants. Premyelinating oligodendrocytes are main building blocks of white matter in preterm infants and vulnerable to oxidative stress and ...
Seung Han Shin   +3 more
doaj   +1 more source

Inflammatory cascades driven by tumor necrosis factor-alpha play a major role in the progression of acute liver failure and its neurological complications. [PDF]

open access: yesPLoS ONE, 2012
Acute liver failure (ALF) due to ischemic or toxic liver injury is a clinical condition that results from massive loss of hepatocytes and may lead to hepatic encephalopathy (HE), a serious neuropsychiatric complication.
Anne Chastre   +5 more
doaj   +1 more source

Fecal microbiota in children with juvenile idiopathic arthritis treated with methotrexate or etanercept

open access: yesPediatric Rheumatology Online Journal, 2021
Background Alterations in the composition of the fecal microbiota in children with juvenile idiopathic arthritis (JIA) have been observed in several studies, but it has not been determined whether the standard treatment for JIA changes the composition or
Anders Öman   +3 more
doaj   +1 more source

The role of tumor necrosis factor-α and natural killer cells in uterine artery function and pregnancy outcome in the stroke prone spontaneously hypertensive rat [PDF]

open access: yes, 2016
Women with chronic hypertension are at increased risk of maternal and fetal morbidity and mortality. We have previously characterized the stroke-prone spontaneously hypertensive rat (SHRSP) as a model of deficient uterine artery function and adverse ...
Beattie, Elisabeth   +6 more
core   +1 more source

Biologic TNF-α inhibitors reduce microgliosis, neuronal loss, and tau phosphorylation in a transgenic mouse model of tauopathy

open access: yesJournal of Neuroinflammation, 2021
Background Tumor necrosis factor-α (TNF-α) plays a central role in Alzheimer’s disease (AD) pathology, making biologic TNF-α inhibitors (TNFIs), including etanercept, viable therapeutics for AD.
Weijun Ou   +10 more
doaj   +1 more source

Long-term safety and efficacy in paediatric psoriasis: Remaining challenges. [PDF]

open access: yesJ Eur Acad Dermatol Venereol
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 4, Page 558-559, April 2026.
Droitcourt C, Goaziou NL.
europepmc   +2 more sources

TCD4pos lymphocytosis in rheumatoid and psoriatic arthritis patients following TNFα blocking agents [PDF]

open access: yes, 2017
BACKGROUND: Lymphocyte expansion and true lymphocytosis are commonly observed in the everyday clinical practice. The meaning of such phenomenon is often poorly understood so that discrimination between benign and malignant lymphocytosis remains ...
Amodeo, Rachele   +11 more
core   +1 more source

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