Results 31 to 40 of about 3,140,461 (306)

A secure IoT-edge architecture with data-driven AI techniques for early detection of cyber threats in healthcare

open access: yesDiscover Internet of Things
The latest developments in the Internet of Medical Things (IoMT) have transformed healthcare, allowing for the easy transmission of sensitive data across networked medical equipment.
Mamta Kumari   +2 more
doaj   +1 more source

Argumentation – Evidentiary Procedure in Criminal Proceedings

open access: yesSEEU Review, 2018
The continuous increase in criminal activities in all countries, namely the offences which undermine the interests of contemporary societies, call for the need to fight them in a more successful manner.
Mehmeti Valon
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Enhancing predictive modeling across industries with automated machine learning: applications in insurance and agriculture

open access: yesDiscover Sustainability
This study explores the efficacy of Automated Machine Learning (AutoML) tools in enhancing linear regression models across industries, focusing on insurance and agriculture.
K. P. Swain   +2 more
doaj   +1 more source

Gluten free approach of biscuits preparation

open access: yesJournal of Agriculture and Food Research, 2023
Replacement of gluten is a challenging issue in preparation of the bakery products. The present work aimed to develop gluten-free biscuits by using gluten-free flours like rice, sorghum, and corn in different ratios (0, 25, 33.33, 50, and 100%).
Deepika Kohli   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

LEGAL PECULIARITIES OF "DIGITALIZATION" OF THE ECONOMY IN THE CONTEXT OF THE DEVELOPMENT OF THE INFORMATION SOCIETY IN UKRAINE

open access: yesBaltic Journal of Economic Studies, 2021
Digitalization of the economy is a determining factor in the growth of the economy as a whole, including the digital industry itself, as a producer of technology. Digital technologies in many sectors are at the core of production strategies.
Maryna Markaryan   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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