Results 191 to 200 of about 6,190 (242)
The Changing Role of Loop Diuretics in Heart Failure Management across the Last Century. [PDF]
Palazzuoli A +7 more
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Diuretic Strategies in Acute Decompensated Heart Failure: A Narrative Review. [PDF]
Wilson BJ, Bates D.
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Drug and therapeutics bulletin, 1966
Ethacrynic acid (Edecrin - MSD), like chlorothiazide, is the product of an intensive search for substances with affinity for sulphydryl groups - a property shown in vitro that is closely linked with clinical diuretic potency. It is an aromatic oxyacetic acid which dissolves poorly in water, well in lipids and is acidic; these properties suggest that it
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Ethacrynic acid (Edecrin - MSD), like chlorothiazide, is the product of an intensive search for substances with affinity for sulphydryl groups - a property shown in vitro that is closely linked with clinical diuretic potency. It is an aromatic oxyacetic acid which dissolves poorly in water, well in lipids and is acidic; these properties suggest that it
+9 more sources
JAMA: The Journal of the American Medical Association, 1970
To the Editor.— In the review article entitled "Acute Renal Failure" by Merrill (211:289, 1970), it is recommended that a test dose of ethacrynic acid as high as 200 mg be given to assist in determining the existence of prerenal failure. I feel that this procedure carries certain definite hazards.
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To the Editor.— In the review article entitled "Acute Renal Failure" by Merrill (211:289, 1970), it is recommended that a test dose of ethacrynic acid as high as 200 mg be given to assist in determining the existence of prerenal failure. I feel that this procedure carries certain definite hazards.
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Furosemide, Bumetanide, and Ethacrynic Acid
Veterinary Clinics of North America: Equine Practice, 1993Furosemide and, less commonly, bumetanide and ethacrynic acid are potent diuretics administered to horses for a variety of reasons, including prophylaxis of exercise-induced pulmonary hemorrhage. These drugs affect urine volume and composition, and furosemide has marked effects on plasma volume and composition and on systemic hemodynamics at rest and ...
K W, Hinchcliff, L A, Mitten
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Ethacrynic acid — Its reversible ototoxicity
The Laryngoscope, 1974AbstractSix cats were intoxicated with an intracardiac injection of ethacrynic acid (30 mg/kg) while being anesthetized with open drop fluothane anesthesia. Twenty‐four hours later the cochlear microphonic and N1 potentials were present and reduced in amplitude, as compared to responses obtained at 48 hours and two and one half months.
H, Silverstein, R, Begin
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Archives of Otolaryngology - Head and Neck Surgery, 1973
Reply We are very grateful to Dr. Cohn for his comments on our article. According to Cohn et al ( Science 171: 910, 1971) and Brusilow ( Fed Proc 31: 298, 1972) low doses (1 to 5 mg/kg) of ethacrynic acid produce an increase of Na+ concentration and a drop of K+ concentration inside the cochlear duct in dogs; however, Silverstein and Yules ...
J. PRAZMA, W. G. THOMAS
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Reply We are very grateful to Dr. Cohn for his comments on our article. According to Cohn et al ( Science 171: 910, 1971) and Brusilow ( Fed Proc 31: 298, 1972) low doses (1 to 5 mg/kg) of ethacrynic acid produce an increase of Na+ concentration and a drop of K+ concentration inside the cochlear duct in dogs; however, Silverstein and Yules ...
J. PRAZMA, W. G. THOMAS
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Cyclic Analog of Ethacrynic Acid
Journal of Pharmaceutical Sciences, 1970The α,β-unsaturated ketone (4,4-dimethyl-2-ethyl-1[4H]-naphthalenon-6-yl)oxyacetic acid (III), a cyclic analog of ethacrynic acid, has been prepared, and its diuretic activity on oral administration to rats and dogs has been evaluated. No significant activity was observed.
M B, Floyd, G R, Allen
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