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Ethanol sensitivity

Annals of Emergency Medicine, 1991
Ethanol sensitivity is a syndrome of flushing, tachycardia, weakness, fatigue, and other dysphoric symptoms in response to relatively small doses of ethanol. We describe a case of extreme ethanol sensitivity presenting with coma and review the pathophysiology of the syndrome.
B, Lerman, R, Bodony
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Ethanol metabolism

Pharmacology & Therapeutics, 1987
Alcohol is metabolized by two pathways in humans: the ADH pathway which accounts for the bulk of the metabolism, and the MEOS pathway which contributes to the increased rate of ethanol elimination at high blood alcohol levels. The increased rate of elimination which results from chronic alcohol consumption is due to an increase in MEOS activity.
D W, Crabb, W F, Bosron, T K, Li
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