Results 211 to 220 of about 1,117,719 (263)
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Critical Reviews in Toxicology, 2003
This article provides a detailed assessment of the toxicological and pharmacological literature concerning alcohol-induced biphasic dose-response relationships. The assessment reveals that alcohol-induced hormetic-like dose-response relationships are commonly observed, highly generalizeable according to model and endpoint and quantitative feature of ...
Linda A. Baldwin, Edward J. Calabrese
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This article provides a detailed assessment of the toxicological and pharmacological literature concerning alcohol-induced biphasic dose-response relationships. The assessment reveals that alcohol-induced hormetic-like dose-response relationships are commonly observed, highly generalizeable according to model and endpoint and quantitative feature of ...
Linda A. Baldwin, Edward J. Calabrese
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Effects of Ethanol and Ethanol Withdrawal on Nociception in Rats
Alcoholism: Clinical and Experimental Research, 1999The effect of acute and chronic administration of ethanol and ethanol withdrawal on a radiant heat tail‐flick assay of nociception was examined in rats. Acute administration of ethanol (2.0 g/kg, ip) produced peak antinociception (68% of maximum) by 30 min, and effects were gone by 120 min.
Harbans Lal, Michael B. Gatch
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Ethanol tolerance and ethanol-drug interactions in the rat
Toxicology and Applied Pharmacology, 1972Abstract Tolerance to the hypnotic effect of ethanol was induced with adifferent time course in adult male and female Holtzman rats by repeated ip administration of ethanol (2.5 g/kg/day). Female rats exhibited tolerance to ethanol after 10 days of treatment and males at 15 days. The extinction of ethanol tolerance was similar in both sexes. Although
Garry K. Hatfield +2 more
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Medical Clinics of North America, 1984
The acute and chronic effects of ethanol on pancreatic structure and function are discussed. Acute necrotizing, acute edematous, acute relapsing, chronic relapsing, and painless pancreatitis have an established association with ethanol abuse. The management of these disorders is outlined.
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The acute and chronic effects of ethanol on pancreatic structure and function are discussed. Acute necrotizing, acute edematous, acute relapsing, chronic relapsing, and painless pancreatitis have an established association with ethanol abuse. The management of these disorders is outlined.
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Ontogeny of ethanol elimination and ethanol-induced hypothermia
Alcohol, 2000Ontogeny of ethanol elimination rates and ethanol-induced hypothermia were examined as possible mechanisms contributing to the marked reduction in ethanol sensitivity early in life (Little et al., 1996; Silveri & Spear, 1998) and the notable gender difference in ethanol sleep-time seen in adult animals (Silveri & Spear, 1998).
Marisa M. Silveri, Linda P. Spear
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Ethanol Clusters in Gasoline-Ethanol Blends
Industrial & Engineering Chemistry Research, 2016Formation of ethanol clusters in gasoline-ethanol fuel blends was studied by pulsed-field-gradient NMR measurement of diffusion of ethanol molecules. The results, consistent with a simple model of clusterization, show that ethanol molecules form hydrogen-bonded clusters with concentration- and temperature-dependent average size.
Anatoly K. Khitrin, Alexander Turanov
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Journal of the American Dietetic Association, 1980
The first step in ethanol metabolism is carried out by two enzyme systems: Alcohol dehydrogenase and cytochrome P-450. The cytochrome P-450 system also detoxifies a wide variety of foreign compounds. On the basis of recent evidence, metabolic reasons are suggested for four well-known consequences of alcoholism: (a) The development of fatty liver; (b ...
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The first step in ethanol metabolism is carried out by two enzyme systems: Alcohol dehydrogenase and cytochrome P-450. The cytochrome P-450 system also detoxifies a wide variety of foreign compounds. On the basis of recent evidence, metabolic reasons are suggested for four well-known consequences of alcoholism: (a) The development of fatty liver; (b ...
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Acute Ethanol Poisoning and the Ethanol Withdrawal Syndrome
Medical Toxicology, 1988Ethanol, a highly lipid-soluble compound, appears to exert its effects through interactions with the cell membrane. Cell membrane alterations indirectly affect the functioning of membrane-associated proteins, which function as channels, carriers, enzymes and receptors.
George H. A. Bone +2 more
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Neurologic Clinics, 1993
Ethanol abuse is associated with a variety of neurologic disturbances. These disturbances result from direct drug effects, drug withdrawal, nutritional deficiency, organ system failure, and other, unidentified factors. In contrast, abuse of sedative-hypnotic drugs produces a more limited spectrum of neurologic involvement, consisting primarily of ...
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Ethanol abuse is associated with a variety of neurologic disturbances. These disturbances result from direct drug effects, drug withdrawal, nutritional deficiency, organ system failure, and other, unidentified factors. In contrast, abuse of sedative-hypnotic drugs produces a more limited spectrum of neurologic involvement, consisting primarily of ...
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Annals of Emergency Medicine, 1991
Ethanol sensitivity is a syndrome of flushing, tachycardia, weakness, fatigue, and other dysphoric symptoms in response to relatively small doses of ethanol. We describe a case of extreme ethanol sensitivity presenting with coma and review the pathophysiology of the syndrome.
B, Lerman, R, Bodony
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Ethanol sensitivity is a syndrome of flushing, tachycardia, weakness, fatigue, and other dysphoric symptoms in response to relatively small doses of ethanol. We describe a case of extreme ethanol sensitivity presenting with coma and review the pathophysiology of the syndrome.
B, Lerman, R, Bodony
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