Results 141 to 150 of about 59,928 (215)

Unspecific Molecular Adsorption (UMA) Sample Preparation Method for Bottom‐up and Whole Protein Analysis: The Foundation

PROTEOMICS, Volume 26, Issue 10, Page 6-15, October 2026.
ABSTRACT The protein sample preparation methods for shotgun proteomics are nowadays well‐established unlike the ones for whole protein analysis. The goal of my work has been to create a simple methodology which provides a single uncomplicated sample preparation tool for these two fields. Nowadays the bulk of proteomics work is done using detergents for
Alexandre Zougman
wiley   +1 more source

Amphiphilic Motif Triggers Microheterogeneity in Low‐Melting Mixtures

Small Structures, Volume 7, Issue 10, October 2026.
Alkylated cholinium iodides are synthesized and mixed with ethylene glycol, resulting in low‐melting mixtures (LMMs). Ammonium alkylation induces amphiphilicity and drives nanoscale segregation into charge‐rich and charge‐poor domains. Combined spectroscopic, scattering, and computational analyses reveal how headgroup alkylation and counterion effects ...
Barbara Rossi, Alessandro Mariani, Mariagrazia Tortora, László Almásy, Arianna Rossetti, Laura Riva, Alessandro Sacchetti, Maria Enrica Di Pietro, Franca Castiglione, Antonino Famulari, Alessandra Del Giudice, Matteo Tommasini, Andrea Lucotti, Barbara Kirchner, Andrea Mele   +14 more
wiley   +1 more source

Repurposing niclosamide ethanolamine for alveolar echinococcosis reveals a disconnect between in vitro efficacy and in vivo outcome in the intraperitoneal infection model. [PDF]

PLoS Negl Trop Dis
Preza M, Dietrich N, Zumstein P, Steinmann J, Hiller L, Zumkehr T, Kämpfer T, Chollet-Krugler M, Vetter L, Hemphill A, Dion S, Lundström-Stadelmann B.   +11 more
europepmc   +1 more source

Targeting Ero1L by Parthenolide Alleviates Cellular Senescence and Fibrosis of Localized Scleroderma by Regulating Mitochondria‐Associated Endoplasmic Reticulum Membranes Stabilization

Aging Cell, Volume 25, Issue 10, October 2026.
PTL inhibits cell senescence and alleviates fibrosis of Los by regulating Ero1L‐mediated mitochondria‐associated endoplasmic reticulum membranes stabilization. ABSTRACT Mitochondrial dysfunction drives scleroderma pathogenesis. The mitochondria‐associated endoplasmic reticulum membrane (MAM) regulates mitochondrial function.
Fei Wang, Ru Xing, Meijuan Xie, Yimin Qin, Yunchao Zhang, Dan Cao, Gu He, Xiaoyan Lyu   +7 more
wiley   +1 more source

Analytical Identification of Novel Furan Metabolites in Human Hepatocytes and Urine: Implications for Liver and Respiratory Disease Research. [PDF]

Chem Res Toxicol
Vevang KR, Trinh A, Schmitt TW, Zhao Y, von Weymarn LB, Meier E, Nomura SO, Robien K, Wang R, Yuan JM, Peterson LA.   +10 more
europepmc   +1 more source

Water, Alcohols, Amines, and Amides as Formal Hydrogen‐Atom‐Transfer Reagents Through Activation With Redox‐Active Lewis Acids

Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.
Protic molecules containing strong O─H or N─H bonds typically resist hydrogen‐atom abstraction because of the high reactivity of the resulting heteroatom‐centered radicals. However, association of the protic molecules with redox‐active Lewis acids can provide powerful hydrogen‐atom donors or proton‐coupled‐electron‐transfer reagents.
Petra Vojáčková, Armido Studer
wiley   +2 more sources

PvrA-Mediated Inhibition of Choline and Ethanolamine Uptake Promotes <i>Pseudomonas aeruginosa</i> Colonization in the Host Environment. [PDF]

Pathogens
Wang S, Yin L, Yang J, Zhang C, Yao Z, Pan X.   +5 more
europepmc   +1 more source

Cobamide excretion allows <i>Salmonella</i> to transition from its anaerobic to aerobic lifestyle. [PDF]

Microbiol Spectr
Malalasekara L, Escalante-Semerena JC.
europepmc   +1 more source

Host–Microbe Mechanisms of Fusobacterium nucleatum in Colorectal Cancer

Molecular Oral Microbiology, Volume 41, Issue 5, Page 258-265, October 2026.
Fusobacterium nucleatum and colorectal cancer. ABSTRACT The oral‐derived pathobiont Fusobacterium nucleatum has increasingly been implicated in colorectal cancer (CRC) progression through its ability to modulate inflammatory, immunological, and molecular pathways. F.
Hadda Lyzandra Austríaco Leite, Fernanda Ferreira Lopes   +1 more
wiley   +1 more source

Biosynthesis of Phosphatidylethanolamine and Phosphatidylcholine via the Kennedy Pathway in Cancer and Other Pathological Conditions. [PDF]

Int J Mol Sci
Korbecki J, Bosiacki M, Chlubek M, Dzięciołowska-Baran E, Lubkowski M, Kabacińska K, Barczak K.   +6 more
europepmc   +1 more source