Results 21 to 30 of about 437,670 (287)
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
BMC PsychiatryIntroduction The management of obsessive–compulsive symptoms (OCS) in patients with schizophrenia is challenging, as many antipsychotics can induce OCS. Increasing evidence supports the use of partial agonists in managing these cases.
Ismail Rammouz +6 more
doaj +1 more source
ATMAN, IDENTITY, AND EMANATION: ARGUMENTS FOR A HINDU ENVIRONMENTAL ETHIC [PDF]
, 2011 Many contemporary authors argue that since certain Hindu texts and traditions claim that all living beings are fundamentally the same as Brahman (God), these texts and traditions provide the basis for an environmental ethic.
Framarin, Christopher G.
core +1 more source
, 2011 Here I argue that the best form of deontology is an ethic of prima facie duties, and that this form of deontology is especially resistant to any form of reduction to a single ...
Stratton-Lake, Philip
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Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
CULTURE AND INSTITUTIONS INTO EVOLUTIONAL ECONOMICS: CONCEPIUAL APPROACH TO THE ANALYSIS
Вестник СибАДИ, 2017 The methodology of the study of the relationship between culture and institutions in economic processes is proposed. Cultural-value system as a special component of the economic reality, contributing to the formation of the institutional shell is ...
V. V. Biryukov, E. V. Romanenko
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim +6 more
wiley +1 more source
Language, Subjectivity and the Agon: A Comparative Study of Nietzsche and Lyotard [PDF]
, 2015 Political Philosophy and ...
Pearson, James S.
core
Advanced Healthcare Materials, EarlyView.The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li +9 more
wiley +1 more source
A systematic analysis of the Polish Code of Medical Ethics
Journal of Education, Health and Sport, 2019 The purpose of this article is to provide a summary of the history which led to the creation of the current structure of the self-regulatory professional body of physicians and dentists, the nature of the professional activities and practice of ...
Anna Augustynowicz +4 more
doaj +1 more source