Results 101 to 110 of about 26,188,763 (291)

The Relationship between Ethical Culture and Unethical Behavior in Work Groups: Testing the Corporate Ethical Virtues Model [PDF]

open access: yes
The Corporate Ethical Virtues Model, which is a model for measuring the ethical culture of organizations, has not been tested on its predictive validity. This study tests the relationship between this model and observed unethical behavior in work groups.
Kaptein, S.P.
core  

Tomada de decisão em bioética clínica: casuística e deliberação moral

open access: yesRevista Bioética
Nos problemas éticos da clínica é preciso apreciar a situação com o uso de procedimentos sistematizados e organizados para a tomada de decisão, visando diminuir as áreas de incerteza caraterísticas dos conflitos de valores e deveres descobertos na ...
Elma Zoboli
doaj  

The current relevance of three classical cases of social research: Milgram, Humphreys, and Zimbardo

open access: yesBioethics Update
Background: Research ethics in social sciences is of great relevance for the protection of participants. Objective: To conduct an ethical analysis of three classic cases of social science research: Milgram’s experiment of obedience to authority ...
Ma. Florencia Santi, Florencia Luna
doaj   +1 more source

GSK-3 Inhibitors and Tooth Repair: An Ethical Analysis

open access: yesFrontiers in Pharmacology, 2019
Tideglusib®, a GSK-3 inhibitor, was initially tested for the treatment of Alzheimer’s disease. However, a recent report has suggested its potential off-label use for the treatment of dental cavities.
Sorin Hostiuc   +4 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Geospatial Ethical Frameworks: A Preliminary Analysis of Current Models

open access: yes
Geospatial technologies have become increasingly ubiquitous in various fields, including (but not limited to) urban planning, environmental management, and disaster response.
Specht, D., Kent, A.J.
core   +1 more source

The Patient's Duty to Adhere to Prescribed Treatment: An Ethical Analysis

open access: yes, 2005
This article examines the ethical basis for the patient's duty to adhere to the physician's treatment prescriptions. The article argues that patients have a moral duty to adhere to the physician's treatment prescriptions, once they have accepted ...
Resnik, David B.
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Nurses contribution to the resolution of ethical dilemmas in context [PDF]

open access: yes
Background: New nursing roles and advances in care and treatments have resulted in nurses facing increasingly complex ethical dilemmas in practice; nurses are therefore required to engage effectively in ethical decision-making.
Barlow, Nichola
core   +2 more sources

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