Results 141 to 150 of about 3,841,126 (310)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
BMC NursingBackground Ethical competence is an essential attribute for professional nurses. Before designing ethics education programmes for nurses, it is crucial to conduct a systematic and accurate analysis of the needs of nurses to optimise the effectiveness of ...
Kyunghee Ha, Younjae Oh
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
PENGAMBILAN KEPUTUSAN ETIS DALAM NOVEL BURLIAN KARYA TERE LIYE: KAJIAN LITERASI MORAL
Bahasa dan Seni: Jurnal Bahasa, Sastra, Seni, dan Pengajarannya, 2019 This research is motivated by three things, namely 1) moral literacy which becomes an ability that needs to be considered in the 21st century, 2) moral literacy which is used to make ethical decisions, and 3) Burlian novel which is one of the literary ...
Akhmad Idris
doaj
BMC Medical EthicsBackground Ethical safety supports the development of ethical competencies and sound decision-making, central to good healthcare practice. The Ethical Safety Questionnaire (ESQ) evaluates ethical safety in healthcare environments, based on three ...
Adrienne Grech +14 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Perceptual mapping of practical ethics along the value chain: A multiple correspondence analysis with industry and cultural indices as supplementary variables [PDF]
This paper presents findings from a study investigating a firm’s ethical practices along the value chain. In so doing we attempt to better understand potential relationships between a firm’s ethical stance with its customers and those of its suppliers ...
Anna Torres +2 more
core