Results 181 to 190 of about 3,841,126 (310)

An Ethical Analysis Regarding the COVID-19 Pandemic Impact on Oral Healthcare in Patients with Mental Disorders. [PDF]

Healthcare (Basel), 2023
Isailă OM, Drima E, Hostiuc S.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Ethical analysis of the change of values in healthcare. [PDF]

Nurs Ethics
Hansen D, Aleksandrova-Yankulovska S, Steger F.   +2 more
europepmc   +1 more source

In-Depth Ethical Analysis of the COVID-19 Vaccine Rollout for Migrant Workers in the Gulf Countries. [PDF]

Int J Soc Determinants Health Health Serv, 2023
Alahmad B, AlMekhled D, Busalacchi K, Wang WC.   +3 more
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Serial Living Solid Organ Donation: An Ethical Analysis. [PDF]

J Eval Clin Pract
Armitage RC.
europepmc   +1 more source

Informed Consent in COVID-19-Research: An Ethical Analysis of Clinical Studies Performed during the Pandemic. [PDF]

Healthcare (Basel), 2023
Voit K, Skuban-Eiseler T, Orzechowski M, Steger F.   +3 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Biomedical ethical analysis of patients' perspectives on posthumous reproduction in a gynecology and obstetrics clinic. [PDF]

BMC Med Ethics
Köken AH, Kara Ö, İnce N, Kara M.
europepmc   +1 more source

How Smart are Smart Materials? A Conceptual and Ethical Analysis of Smart Lifelike Materials for the Design of Regenerative Valve Implants. [PDF]

Sci Eng Ethics, 2023
de Kanter AJ, Jongsma KR, Bouten CVC, Bredenoord AL.   +3 more
europepmc   +1 more source