Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Stimulating Regulatory Compliance and Ethical Behavior of Organizations: A Review [PDF]
Business Ethics and LeadershipRegulators are responsible for overseeing organizations. Organizational behavior should be in line with laws and regulations. Therefore, regulators aim to influence behavior of regulatees, such as compliance (i.e., following rules and regulations), but ...
Sarwesh Ishwardat +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Exploring the Influence of Artificial Intelligence Usage on Ethical Decision Making Among Public Sector Employees: Insights into Moral Identity and Service Motivation [PDF]
Business Ethics and LeadershipThis study constructs a moderating mediation model to link public sector employees’ Artificial Intelligence (AI) usage with employees’ moral norms and ethical decision-making behaviors.
Xiangyu Bian, Bin Wang
doaj +1 more source
Physiotherapists' ethical behavior in professional practice: a qualitative study. [PDF]
Front Med (Lausanne), 2023 Mármol-López MI +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Employee Perception of Ethical Behavior of the Leadership within a Nonprofit Organization
, 2016 Many leaders of organizations who were once thought of as highly regarded companies have been under intense criticism for their lack of clear ethical accountability across the board. While even the most profitable organization can run the risk of failing
Goode, Kimberly R.
core +1 more source
Teaching Ethics in an Unethical World
Annales Etyka w Życiu Gospodarczym, 2017 We find ourselves in times where national leaders engage in fraudulent and deceptive behaviors for personal and political gains, and multinational corporations use unethical practices to maximize their profits.
Sharaf N. Rehman
doaj +1 more source
Psychometric testing of the Indonesian version of the Nurses' Ethical Behavior in Protecting Patients' Rights (I-NEBPPR) scale. [PDF]
Belitung Nurs J, 2023 Susmarini D, Ninh DT, Li C, Lee G.
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source