Results 221 to 230 of about 6,904,670 (284)

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini   +12 more
wiley   +1 more source

Evaluation of Statement Accuracy on Ethical Decision-Making. [PDF]

open access: yesBehav Anal Pract
Brodhead MT, Cascarilla AN, Cox DJ.
europepmc   +1 more source
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Ethics and Administrative Decision Making

JONA: The Journal of Nursing Administration, 1987
Ethical issues in administrative decision making pose a critical problem for nurse executives in a changing health care environment. A study of all the acute care hospitals in one state reveals an identified ethical component to nursing administrative practice.
M R, Sietsema, B W, Spradley
openaire   +2 more sources

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