Results 131 to 140 of about 6,978,543 (287)

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Ethical Sustainability in Organizational Decision-Making

Sustainable decision-making, which involves choosing alternatives that meet present needs without compromising the future, has gained significant importance in light of the increasing social and environmental concerns.
Makki, Sonia J., Gil Doménech, Maria Dolors, Bastons, Miquel, Selvam, Rejina Mary   +3 more
core   +1 more source

Ethical decision-making under stress: the role of the nonreactive facet of mindfulness. [PDF]

Front Psychol
Hanson SK, Hollingworth D, Valentine SR.
europepmc   +1 more source

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

FEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source

Frailty Scores and Ethical Decision-Making in Critical Care: Lessons From the COVID-19 Pandemic. [PDF]

Clin Case Rep
Elendu C, Okezie-Okoye CA, Ali AI, Okolo EH, Bell-Gam MA, Ravikumar K, Mbakwe FK.   +6 more
europepmc   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Operational Ethics in the Cardiovascular Intensive Care Unit: A Practical Framework for Ethical Decision-Making. [PDF]

J Clin Med
Vicent L, Salguero-Bodes R, R Alonso P, Puerto E, Diaz-Arocutipa C, Arribas Ynsaurriaga F, Martín-Asenjo R.   +6 more
europepmc   +1 more source

THE INFLUENCE OF ETHICAL LEADERSHIP THROUGH DECISION MAKING AND REINFORCEMENT TOWARDS EMPLOYEE OUTCOMES [PDF]

Journal of Applied Structural Equation Modeling, 2019
Umi Hamidaton Mohd Soffian Lee, Razaleigh Muhamat @ Kawangit , Zaleha Yazid   +2 more
doaj   +1 more source

Ethical Decision-Making in Entrepreneurial Dentistry: An Exploratory Conceptual Framework Informed by Romanian Healthcare Studies. [PDF]

Dent J (Basel)
Constantin GD, Cucui-Cozma A, Veja I, Mazilescu CA, Oancea R.   +4 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source