Results 221 to 230 of about 6,978,543 (287)

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Ethics Discourse in a Recurring Journal Format: A Proposal to Increase Ethics Discussion and Supports for Ethical Decision-Making. [PDF]

Behav Anal Pract
Quigley SP, Weiss MJ, Zane T, Graber A.
europepmc   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Flavio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source

Medical futility at the end of life: the first qualitative study of ethical decision-making methods among Turkish doctors. [PDF]

BMC Med Ethics
Aksoy E, Ilkilic I.
europepmc   +1 more source

Evaluation of Statement Accuracy on Ethical Decision-Making. [PDF]

Behav Anal Pract
Brodhead MT, Cascarilla AN, Cox DJ.
europepmc   +1 more source

Ethical Decision-Making for Self-Driving Vehicles: A Proposed Model & List of Value-Laden Terms that Warrant (Technical) Specification. [PDF]

Sci Eng Ethics
Poszler F, Geisslinger M, Lütge C.
europepmc   +1 more source

The relationship and influencing factors of critical thinking and medical ethical decision-making among pediatric medical students. [PDF]

Medicine (Baltimore)
Dang H, Li S, Li J.
europepmc   +1 more source

Applying AVWEWM to ethical decision-making during autonomous vehicle crashes. [PDF]

Sci Rep
Liu G, Luo Y, Sheng J.
europepmc   +1 more source

Ethical decision-making

, 2023
Abstract This chapter covers ethical decision making. It begins with an introduction of how to apply the principles discussed in the chapter. It then describes approaches to medical ethics, the development of codes, and clinical ethics committees. It goes on to approaches to ethical reasoning, including utilitarianism, deontology, virtue
Nigel Eastman, Gwen Adshead, Simone Fox, Richard Latham, Seán Whyte, Hannah Kate Williams   +5 more
core   +3 more sources