Results 31 to 40 of about 36,371 (263)

Ethical Dilemmas, Causes, and Countermeasures of Centralized Drug Procurement

open access: yesYixue yu zhexue
Centralized drug procurement is a key initiative in healthcare system reform. While it has successfully reduced costs and benefited the public, it has also triggered a range of ethical challenges.
Qiang XIONG
doaj   +1 more source

Who decides in withdrawal of treatment in a critical care setting? A case study on ethical dilemma

open access: yesInternational Journal of Nursing Sciences, 2018
Case description: Withdrawal of treatment is a common practice in critical care settings, perticularly when treatment is considered futile. The case study demonstrates an ethical dilemma, in which Danny is unlikely to make a functional recovery because ...
Chunmei Lyu, Li Zhang
doaj   +1 more source

Deciphering Anti‐Cancer Drug Efficacy Through Nanomechanical Vibrations in Living Gastric Cancer Organoids

open access: yesAdvanced Science, EarlyView.
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang   +10 more
wiley   +1 more source

Ethical Dilemmas and Governance Strategies for Research and Clinical Application of Proton Tumor Therapy

open access: yesYixue yu zhexue
Throughout the process from research and development to clinical translation, proton therapy for tumors continues to face unresolved issues regarding the management of safety risks and the attribution of responsibility.
Wen CAO, Wenbing MA, Shiyun ZHANG
doaj   +1 more source

Digital Dilemma 2018

open access: yesPapers from the Institute of Archaeology, 2020
To download this paper, please click here.In October 2018 a one-day conference was held at the UCL Institute of Archaeology focussing on the ‘Digital Dilemma’ in biological archaeology —specifically human remains research where the use of digitisation ...
doaj   +2 more sources

Nanometer Layer Coating to Lactose Particles for Optimization of Dexamethasone Pulmonary Delivery

open access: yesAdvanced Science, EarlyView.
Nanometer layer coating (NLC) was investigated and its mechanism illustrated by advanced characterization techniques. The effects and application for the inhalation of dexamethasone (DEX) were demonstrated through in vitro and in vivo evaluation. This approach increased DEX bioavailability and enabled the dose to be reduced to 1/30 of the intravenous ...
Qin Nie   +11 more
wiley   +1 more source

GenEth: a general ethical dilemma analyzer

open access: yesPaladyn, 2018
We argue that ethically significant behavior of autonomous systems should be guided by explicit ethical principles determined through a consensus of ethicists. Such a consensus is likely to emerge in many areas in which intelligent autonomous systems are
Anderson Michael, Anderson Susan Leigh
doaj   +1 more source

To Overcome Ethical Dilemmas in an Organization: Paradox and Ethics of Freedom Can Help [PDF]

open access: yesBusiness Ethics and Leadership
A theoretical model for managers responding to a morally challenging situation is developed in the article. This model explores and examines how managers deal with paradoxes created by ethical dilemmas.
Benoît Cherré, Nathalie Lemieux
doaj   +1 more source

Whistleblowing: an ethical dilemma

open access: yesAustralasian Journal of Information Systems, 1993
Because most organizations depend on computer systems that electronically store important data to perform crucial business functions, the integrity of these information systems is paramount. Securing company systems, however, is not always an easy task.
Joan K. Pierson   +2 more
openaire   +3 more sources

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

open access: yesAdvanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang   +14 more
wiley   +1 more source

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