Results 41 to 50 of about 335,789 (283)

The problem of lesser evil within the context of public health

Journal of Education, Health and Sport, 2016
Sytnik-Czetwertyński Janusz, Cianciara Dorota. The problem of lesser evil within the context of public health. Journal of Education, Health and Sport. 2016;6(10):299-308. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.162532 http://ojs.ukw.edu.pl/
Janusz Sytnik-Czetwertyński, Dorota Cianciara   +1 more
doaj   +3 more sources

Ethical Dilemmas, Causes, and Countermeasures of Centralized Drug Procurement

Yixue yu zhexue
Centralized drug procurement is a key initiative in healthcare system reform. While it has successfully reduced costs and benefited the public, it has also triggered a range of ethical challenges.
Qiang XIONG
doaj   +1 more source

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

Artificial intelligence and healthcare: An ethical dilemma

Bangabandhu Sheikh Mujib Medical University Journal, 2023
not available Bangabandhu Sheikh Mujib Medical University Journal 2023;16(2): 73 ...
Zubair Ahmed Ratan , Md Atiqul Haque
doaj   +1 more source

A Voting-Based System for Ethical Decision Making [PDF]

, 2018
We present a general approach to automating ethical decisions, drawing on machine learning and computational social choice. In a nutshell, we propose to learn a model of societal preferences, and, when faced with a specific ethical dilemma at runtime ...
Awad, Edmond, Dsouza, Sohan, Gaikwad, Snehalkumar 'Neil' S., Noothigattu, Ritesh, Procaccia, Ariel D., Rahwan, Iyad, Ravikumar, Pradeep   +6 more
core   +3 more sources

Covert research and adult protection and safeguarding: An ethical dilemma? [PDF]

, 2014
Purpose: This paper aims to consider the contentious issue of covert research in studying the social contexts of vulnerable groups. It explores its potential utility in areas where overt strategies may be problematic or denied; and examines and ...
Ashencaen Crabtree, Sara, Parker, Jonathan   +1 more
core   +1 more source

NIR Light‐Driven Photocatalytic Antibacterial Hydrogels for Synergistic MRSA Biofilm Eradication and Wound Regeneration

Advanced Science, EarlyView.
The nanohybrid hydrogel (Fe‐BOS@C/H Gel) is composed of Fe‐Bi2O2‐XS (Fe‐BOS) photocatalysts and CS‐ADH/OHA (C/H) hydrogel. Fe‐BOS photocatalysts achieve near‐infrared (NIR) light‐driven antibacterial photocatalytic/mild photothermal therapy (APCT/MPTT), effectively eliminating methicillin‐resistant Staphylococcus aureus (MRSA) biofilms. The degradation
Dong Mo, Yujia Wei, Meng Pan, Wen Chen, Yun Yang, Kang Li, Xicheng Li, Jianan Li, Qingya Liu, Hanzi Deng, Mei Zhu, Zhenpeng Zhang, Zhaolin Xiao, Zhiyong Qian   +13 more
wiley   +1 more source

PENGARUH PENGALAMAN AUDITOR DAN ETIKA PROFESI TERHADAP PENYELESAIAN DILEMA ETIKA : Studi Pada Auditor di Kantor Akuntan Publik di Kota Bandung [PDF]

, 2015
Penelitian ini bertujuan untuk mengetahui apakah pengalaman auditor berpengaruh positif atau tidak terhadap penyelesaian dilema etika di Kantor Akuntan Publik di Kota Bandung dan untuk mengetahui apakah etika profesi berpengaruh positif atau tidak ...
Saraswati, Melani
core  

Targeting PRKCN, an Essential Driver Orchestrating mTOR‐IRF4 Axis Independently of Kinase Activity, in Multiple Myeloma

Advanced Science, EarlyView.
Constitutive PRKCN expression is driven by super‐enhancers and modulated by NF‐κB signaling in multiple myeloma (MM). PRKCN activates mTORC1/2‐IRF4 signaling axis and favors tumor cell growth independently of its kinase activity. IRF4 reciprocally promotes PRKCN transcription, creating a feed‐forward loop.
Koukou Tang, Dongpeng Jiang, Peng Ke, Xiaosen Bian, Lili Zhang, Ying Zhang, Tingting Zhu, Weiwei Qu, Wenhui Qi, Yang Xu, Chengcheng Fu, Depei Wu, Jianhong Chu   +12 more
wiley   +1 more source

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source