Results 31 to 40 of about 28,657 (213)
Advanced Science, EarlyView.A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li +13 more
wiley +1 more source
Dilemmas in Antenatal Reporting of Ambiguous Genitalia on Ultrasound, under Preconception and Prenatal Diagnostic Techniques Act, 1994 [PDF]
Journal of Clinical and Diagnostic ResearchDear Editor, Author has written this letter to express her concern regarding the recent developments in the implementation of the Preconception and Prenatal Diagnostic Techniques (PCPNDT) Act.
Karishma Santosh Krishnani
doaj +1 more source
Advanced Science, EarlyView.A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong +13 more
wiley +1 more source
Advanced Science, EarlyView.This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang +10 more
wiley +1 more source
RUDN Journal of Philosophy, 2015 The article is devoted to moral dilemmas of such phenomenon of modern science as cloning in order to investigate possible perspectives based on moral norms in the society.
E V Maximova
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Health Services InsightsThe provision of long-term care services for older adults is characterised by increasing needs and scarce resources, leading to ethical dilemmas. This qualitative study explored the ethical dilemmas experienced by healthcare professionals when allocating
Ann Katrin Blø Pedersen +2 more
doaj +1 more source
Nanometer Layer Coating to Lactose Particles for Optimization of Dexamethasone Pulmonary Delivery
Advanced Science, EarlyView.Nanometer layer coating (NLC) was investigated and its mechanism illustrated by advanced characterization techniques. The effects and application for the inhalation of dexamethasone (DEX) were demonstrated through in vitro and in vivo evaluation. This approach increased DEX bioavailability and enabled the dose to be reduced to 1/30 of the intravenous ...
Qin Nie +11 more
wiley +1 more source
Zdravniški Vestnik, 2009 Background Ethical dilemmas are an important part of daily routine in family practice. One of the options for better quality in family practice is also an effective postgraduate education in the field of bioethics.
Zalika Klemenc-Ketiš +2 more
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Farmers' Preferences for Gene Editing Crops and Influencing Factors
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT Gene editing (GE) is gaining momentum worldwide, but limited data on UK farmers' preferences hinders our understanding of its potential impact amid deregulation debates. Based on a survey of 200 English arable farmers, we employ a Latent Class Analysis and Multinomial Logit regressions to investigate current preferences for GE crops.
Bertolozzi‐Caredio Daniele +1 more
wiley +1 more source
Fysioterapeuten, 2015 Purpose: Working with elderly, frail stroke patients may provide complex professional challenges. This article is based upon a thesis about physiotherapists’ experiences with ethical dilemmas and ethical reflections in their work with these patients and ...
Kristin Fiskaa
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