Results 81 to 90 of about 2,148,458 (311)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Ethics Brewed in an African Pot [PDF]

open access: yes, 2011
Doing ethics in African Christianity raises the challenge of over-generalization in the midst of diversity and variety. This essay surveys the wide ethical landscape of Africa, explores key ethical issues on the continent within the context of the world ...
Orobator, Agbonkhianmeghe E.
core   +1 more source

Deep Cover HCI [PDF]

open access: yes, 2015
The growing popularity of methodologies that turn "to the wild" for real world data creates new ethical issues for the HCI community. For investigations questioning interactions in public or transient spaces, crowd interaction, or natural behaviour ...
Festinger L., Fine G. A, Parker, Robbins
core   +1 more source

Ethical issues in health promotion

open access: yesSouth African Journal of Bioethics and Law, 2017
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Jillian Gardner
doaj   +1 more source

Resource Guide in Exploring Ethics: A Practical Resource Guide for Tutors and Students [PDF]

open access: yes, 2009
This resource guide will help staff and students who are studying social sciences in hospitality, tourism, entertainment, events, leisure. It outlines the ethical issues that they need to consider when conducting research for their dissertation or for ...
Kenyon, AJ, Wood, E
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Perception of and attitude toward ethical issues among Korean occupational physicians

open access: yesAnnals of Occupational and Environmental Medicine, 2017
Background Occupational physicians (OPs) have complex relationships with employees, employers, and the general public. OPs may have simultaneous obligations towards third parties, which can lead to variable conflicts of interests.
Junghye Choi   +11 more
doaj   +1 more source

Ethical investment in superannuation funds; Can it occur without breaching traditional trust principles? [PDF]

open access: yes, 2009
Ethical investing in commercial activities is a topic which has received considerable attention of late. This has occurred in the areas of company law at all levels, with the concerns of consumers in relation to the production of products, and also in ...
Tennent, Douglas
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Ethical Issues Faced by Registered Nurses at Selected Public Clinics of Mopani District, Limpopo Province, South Africa

open access: yesProceedings
Background: Ethics is an integral part of the nursing profession, forming the foundation thereof [...]
Tsakani Agnes Nyambi   +2 more
doaj   +1 more source

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