Results 51 to 60 of about 1,314,449 (310)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Analysis of the Relationship Between Ethical Leadership and Cooperative Social Responsibility and the Organization\'s Moral Climate [PDF]

open access: yesInternational Journal of Ethics and Society
Introduction: Ethical leadership is leadership focused on appropriate behavior through respect for ethics and values, as well as the rights and dignity of others.
Prata Arpa, Rahil Sondak, Sardan Ostrich
doaj  

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Credit Markets with Ethical Banks and Motivated Borrowers [PDF]

open access: yes
This paper investigates banks’ corporate social responsibility. Two different competitive credit markets do exist: one for standard projects and one for ethical ones.
Barigozzi, Francesca, Tedeschi, Piero
core   +3 more sources

Ethical Responsibility vs. Ethical Responsiveness in Conscious and Unconscious Communication Agents

open access: yesProceedings, 2020
In this contribution, I start from Levy’s precious suggestion about the neuroethics of distinguishing between “the slow-conscious responsibility” of us as persons, versus “the fast-unconscious responsiveness” of sub-personal brain mechanisms studied in ...
Gianfranco Basti
doaj   +1 more source

Futural Dispatches on Responsibility for the Earth, or, ‘What on Earth Is Ethical Responsibility?’

open access: yesHumanities, 2022
This article explores the question of the limits of ethical responsibility in the context of the contemporary ecological crisis. Drawing centrally on a selection of writings by Jacques Derrida, Emmanuel Levinas and, in the second half of the article ...
Dave Boothroyd
doaj   +1 more source

In Breakable Glasses: Toward a Naturalist Orientational Cosmology [PDF]

open access: yes, 2005
The author develops the formula, "that process that gives rise to all that exists," as a specification of the cosmos within which human life may find meaningful, ethical orientation.
Bernard, Danièle   +2 more
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

On Responsibility: Islamic Ethical Thought Engages with Jewish Ethical Thought

open access: yesReligions
A remarkable amount of work on the study of Islamic ethical thought is published annually, covering an unprecedented variety of topics and themes. Yet despite the strides made, these debates have not addressed vital questions about how Islamic ethical ...
Ufuk Topkara
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy