Results 201 to 210 of about 12,286,533 (342)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Approved Ambiguities: An Analysis of Applications for the Ethical Review of Animal Research in Sweden-Focusing on Harm, Benefit, and the 3Rs. [PDF]

Animals (Basel)
Jörgensen S, Weber EM, Lindsjö J, Lundmark Hedman F, Röcklinsberg H.   +4 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Global comparison of research ethical review protocols: insights from an international research collaborative. [PDF]

BJU Int
Chow BJ, Light A, Nathan A, Baekelandt L, Marcq G, Croghan S, Gaba F, Esperto F, Orecchia L, Toribio-Vázquez C, Gómez Rivas J, Fung AC, Gebreselassie KH, Felicio E, Danurdoro A, Pyrgidis N, Marko V, Svihra J, Javid M, Salas A, Thanh TT, Alexander C, Bhatt N, Khadhouri S, Kasivisvanathan V, Byrnes K, British Urology Researchers in Surgical Training (BURST) in collaboration with the European Association of Urology Young Academic Urologists Urothelial Carcinoma Working Group.   +26 more
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

The inconsistent ethical oversight of healthcare quality data in Switzerland

Swiss Medical Weekly, 2018
Stuart McLennan, Roxanne Maritz, David Shaw, Bernice Elger   +3 more
doaj   +1 more source

Resources to aid ethical review of clinical studies: an exploratory scoping review identifying gaps and opportunities. [PDF]

Trials
Pittelkow MM, Strech D.
europepmc   +1 more source

Scientific Review by the Ethics Committee [PDF]

Journal of Empirical Research on Human Research Ethics, 2014
Jeffrey A, Cooper, Lindsay, McNair
openaire   +2 more sources

Ethics Review for Case Studies

Current Medical Issues, 2022
Sirshendu Chaudhuri, Kapil Goel, Aniruddha Basu   +2 more
openaire   +2 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source