Results 91 to 100 of about 38,041 (341)

Taking Free Will Skepticism Seriously [PDF]

open access: yes, 2012
An apparently increasing number of philosophers take free will skepticism to pose a serious challenge to some of our practices. This must seem odd to many—why should anyone think that free will skepticism is relevant for our practices, when nobody seems ...
Vilhauer, Benjamin
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Do Virtue Ethicists Parent Poorly?

open access: yesFeminist Philosophy Quarterly
In this paper, I argue that virtue ethics is unfortunately committed to a developmentally detrimental form of moral evaluation in its traditional iterations.
J. B. Delston
doaj  

Policymakers' engagement with ethicists to improve public health in the United States

open access: yesPreventive Medicine Reports
Objective: To determine how policymakers interact with bioethicists, their interest in future engagement, and their motivation and hesitations to do so.
Adam Seth Levine, Andrew G. Shuman
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Supererogatory Spandrels [PDF]

open access: yes, 2017
Standing in San Marco Cathedral in Venice, you immediately notice the exquisitely decorated spandrels: the triangular spaces bounded on either side by adjoining arches and by the dome above.
Benn, Claire
core   +1 more source

Accidental rightness [PDF]

open access: yes, 2009
In this paper I argue that the disagreement between modern moral philosophers and (some) virtue ethicists about whether motive affects rightness is a result of conceptual disagreement, and that when they develop a theory of ‘right action,’ the two ...
van Zyl, Liezl
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Discussion of "Statistical Inference: The Big Picture" by R. E. Kass

open access: yes, 2011
Discussion of "Statistical Inference: The Big Picture" by R. E. Kass [arXiv:1106.2895]Comment: Published in at http://dx.doi.org/10.1214/11-STS337A the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical Statistics (http:
Goodman, Steven N.
core   +3 more sources

Margaret Cavendish, Feminist Ethics, and the Problem of Evil [PDF]

open access: yes, 2018
This paper argues that, although Margaret Cavendish’s main philosophical contributions are not in philosophy of religion, she makes a case for a defense of God, in spite of the worst sorts of harms being present in the world.
Hernandez, Jill
core   +2 more sources

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