Results 101 to 110 of about 38,041 (341)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Key Insights and Priorities for Evaluating the Effectiveness of Clinical Ethics Consultation
Canadian Journal of BioethicsDuring the 2023 Canadian Bioethics Society forum, 28 practicing healthcare ethicists (PHEs) and other attendees from across Canada, including bioethics students and fellows, gathered virtually for a collaborative workshop entitled “Towards Evaluating ...
Lauren Honan +4 more
doaj +1 more source
In die Skriflig, 2014 On 20 May 2010, the Venter Institute in America announced that they have fully synthesised the genome of the organism Mycoplasma mycoides whilst in vitro by using a computer connected to a machine that synthesises genes. Thereafter, the genome was placed
Riaan A.L. Rheeder
doaj +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
The Desire for Happiness and the Virtues of the Will
Journal of Moral Theology, 2014 Recent developments in moral philosophy have provided new opportunities to reconsider Thomas Aquinas’ theory of virtue and its relation to happiness. Specifically: Thomas’ foundational point in the prima pars of man’s universal desire for happiness is ...
Jean Porter
doaj
Ethical Considerations for Movement Mapping to Identify Disease Transmission Hotspots
Emerging Infectious Diseases, 2019 Traditional public health methods for detecting infectious disease transmission, such as contact tracing and molecular epidemiology, are time-consuming and costly.
Bouke C. de Jong +17 more
doaj +1 more source
It’s Worth What You Can Sell It for: A Survey of Employment and Compensation Models for Clinical Ethicists [PDF]
, 2023 Jason Adam Wasserman +2 more
openalex +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source