Results 81 to 90 of about 3,310,200 (292)
Ethics in Clinical Development [PDF]
Journal of the Royal Society of Medicine, 1990 The meeting was convened to provide a forum for the discussion of those aspects of medical ethics which concerned clinical research, particularly the clinical studies which the pharmaceutical industry is required to carry out to satisfy regulatory authorities for them to issue licences for the introduction of new medicines.
openaire +2 more sources
Rethinking the therapeutic misconception: social justice, patient advocacy, and cancer clinical trial recruitment in the US safety net. [PDF]
, 2014 BackgroundApproximately 20% of adult cancer patients are eligible to participate in a clinical trial, but only 2.5-9% do so. Accrual is even less for minority and medically underserved populations. As a result, critical life-saving treatments and quality
Burke, Nancy J
core +3 more sources
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
A Short Review of Ethical Challenges in Clinical Natural Language Processing
, 2017 Clinical NLP has an immense potential in contributing to how clinical practice will be revolutionized by the advent of large scale processing of clinical records. However, this potential has remained largely untapped due to slow progress primarily caused
Daelemans, Walter +2 more
core
Real Virtuality: A Code of Ethical Conduct. Recommendations for Good Scientific Practice and the Consumers of VR-Technology [PDF]
, 2016 The goal of this article is to present a first list of ethical concerns that may arise from research and personal use of virtual reality (VR) and related technology, and to offer concrete recommendations for minimizing those risks.
Madary, Michael, Metzinger, Thomas
core +3 more sources
Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja +8 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Tomada de decisão em bioética clínica: casuística e deliberação moral
Revista BioéticaNos problemas éticos da clínica é preciso apreciar a situação com o uso de procedimentos sistematizados e organizados para a tomada de decisão, visando diminuir as áreas de incerteza caraterísticas dos conflitos de valores e deveres descobertos na ...
Elma Zoboli
doaj
STUDIES ON BIOCHEMICAL CHANGES AND THERAPEUTIC MANAGEMENT OF METABOLIC SYNDROME IN DOGS [PDF]
Journal of Veterinary and Animal Sciences, 2017 Twelve obese dogs with metabolic syndrome were treated with ezetimibe @ 0.1mg/ kg bodyweight for a period of 30 days.
Siji.S.Raj +5 more
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