Results 111 to 120 of about 1,331,219 (244)

Fully Automated Deep Learning Enabled Miniature Mass Spectrometry System for Psychoactive Therapeutic Drug Monitoring

open access: yesAdvanced Science, EarlyView.
This study presents a fully automated miniature mass spectrometry system for high‐throughput therapeutic drug monitoring. Integrating magnetic solid‐phase extraction, self‐aspiration sampling miniature mass spectrometer, and U‐net deep learning quantitative algorithm, it achieves rapid (8 samples/30 min), precise (R2 > 0.99, RSD < 10%), and portable ...
Yuanhao Zhou   +10 more
wiley   +1 more source

HLA‐DR⁺ Tumor Cells Show an Association with a Distinct Immune Microenvironment and CD8⁺ T‐Cell Exhaustion in HBV‐Associated Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
This study integrates scRNA‐seq, multiplex immunofluorescence, and clinical data to identify HLA‐DR⁺tumor cells uniquely enriched in Hepatocellular carcinoma (HCC) with hepatitis B virus (HBV). These cells express MHC II, associate with PD‐L1, recruit and exhaust CD8⁺T cells, predict poor survival, and serve as potential biomarkers for immunotherapy ...
Jun‐Qing Chang   +17 more
wiley   +1 more source

The Attention Rate of Librarians in Isfahan University of Medical Sciences and Isfahan University to Professional Ethics based on Ethical Codes of Iranian University Librarians

open access: yesمدیریت اطلاعات سلامت, 2012
• Introduction: The most important variable in success of every organization is attention to ethics. Since library and information sciences naturally involve service provision to users, commitment to professional ethics is necessary.
Zahra Kazempour   +2 more
doaj  

Concept of Moral and Etics in The Profession of Judges When Making Decission in A Case

open access: yesMetro Islamic Law Review, 2022
Discourses about professional ethics of judges started out from the reality of law enforcement officials (especially judges) that ignore the values of morality.
Rina Aggraini   +3 more
doaj  

Training‐Free Regulation of Grasping by Intracortical Tactile Feedback Designed via S1‐M1 Communication

open access: yesAdvanced Science, EarlyView.
During object grasping in macaques, information flow between the primary sensory cortex (S1) and the primary motor cortex (M1) is modulated by tactile properties of the target. Intracortical micro‐stimulation in S1 reliably evokes M1 responses that resemble those naturally generated during grasping under specific tactile conditions.
Qi Zhang   +9 more
wiley   +1 more source

Identification of Schwann Cells in Human Intracranial Arteries: Potential Regulatory Role in Atherosclerotic Plaque Progression

open access: yesAdvanced Science, EarlyView.
Schwann cells may facilitate intracranial plaque progression via neurovascular remodelingcting with vascular smooth muscle cells in atherosclerotic plaques, with the SPP1 ‐ ITGB1 signaling axis mediating this interaction as a novel mechanism. Abstract Intracranial atherosclerosis (ICAS), a common cause of ischemic stroke, remains a therapeutic ...
Zijue Wang   +10 more
wiley   +1 more source

AI‐Driven Defecation Analysis by Smart Healthcare Toilet: Exploring Biometric Patterns and Eu‐Tenesmus

open access: yesAdvanced Science, EarlyView.
A healthcare toilet system is introduced to passively measure defecation behavior. Real‐time data on stool dropping duration, thickness, and a newly defined “eu‐tenesmus” interval show correlations with stool form and gender differences. Results from 45 defecation events reveal a promising method for comprehensive defecation analysis.
Zhiquan Song   +16 more
wiley   +1 more source

The Attitudes of Librarians in Hamadan Public Libraries Regarding the Professional Ethics [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2014
Purpose: The aim of this study is to examine the level of familiarity with professional ethics demonstrated by librarians in Hamadan public libraries, and to determine the factors affecting these librarians' attitudes towards professional ethics and ...
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doaj  

A Novel nor@DHB Matrix for Direct Microbial Analysis in Lung Cancer Tissues

open access: yesAdvanced Science, EarlyView.
Integrated matrix‐assisted laser desorption/ionization mass spectrometry workflow quantifies intratumoral microbes in lung cancer through lipopolysaccharide/lipid A extraction from biopsies. The novel ionic matrix called norharmane conjugated to 2,5‐dihydroxybenzoic acid enhances lipid A ionization, enabling direct detection of bacterial genera ...
Liang Shan   +12 more
wiley   +1 more source

A Wearable AI‐Driven Mask with Humidity‐Sensing Respiratory Microphone for Non‐Vocal Communication

open access: yesAdvanced Science, EarlyView.
A wearable, plug‐and‐play respiratory microphone—featuring a gold nanoparticle‐based humidity sensor—facilitates voice‐free verbal communication for patients with impaired vocal fold function. Abstract Hoarseness and dysphonia caused by vocal cord conditions or laryngeal surgeries significantly hinder communication and quality of life.
Jianfei Wang   +8 more
wiley   +1 more source

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