Results 111 to 120 of about 69,237,434 (254)

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Does Germany Need a (New) Research Ethics for the Social Sciences? [PDF]

open access: yes
This paper evaluates the German, UK, and US approaches to dealing with research ethics in the social sciences. It focuses 1) on the extent to which these research ethic frameworks protect the key rights of research subjects and 2) the extent to to which ...
Eva Wegner, Claudia Oellers
core  

Through the eyes of Spanish-speaking patients, caregivers, and community leaders: a qualitative study on the in-patient hospital experience

open access: yesInternational Journal for Equity in Health
Background Spanish-speakers with non-English language preference and complex medical needs suffer disparities in quality of care, safety, and health outcomes.
Nicholas V. Nguyen   +6 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

MANUAL FOR RESEARCH ETHICS COMMITTEES

open access: yes, 2003
Editorial board -- Acknowledgements -- List of contributors - - Introduction / Sue Eckstein -- Pt. 1. Section I. Fundamental ethical and legal considerations -- Ch. 1. The ethics of clinical research / Calliope (Bobbie) Farsides -- Ch. 2.
Eckstein, Sue, ed.   +1 more
core  

Un projet de recherche exempté d’évaluation éthique : une suggestion de clarification sur le processus d’évaluation éthique

open access: yesBioéthiqueOnline, 2013
This letter proposes a clarification regarding the use of the TCPS2 for ethics review in response to the exemption from review of a specific research proposal by the research ethics board of the organisation.
Caillé, Jean, Beauregard, Guy
doaj  

Relational ethics between researchers: An Indigenous qualitative perspective

open access: yesMethods in Psychology
Qualitative research has long emphasized the ethics of researcher-participant relationships, however far less attention has been given to the ethical complexities of relationships between research collaborators.
Gloria Fraser
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

දිවි තොරකර ගැනීම් සහ දෝෂාරෝපණයන්: ආචාර ධාර්මික මාධ්‍යකරණයද?

open access: yes, 2021
On March 01,2021 Sunday Observer reported on suicide in a manner that did not comply with media ethics ...
Ethics Eye
core  

Un projet de recherche exempté d’évaluation éthique : quelques précisions

open access: yesBioéthiqueOnline, 2013
This piece responds to the comments made by Caillé and Beauregard by offering clarifications regarding the exemption from ethics review of a research project.
Durand, Céline, Fortin, Marie-Chantal
doaj  

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