Results 1 to 10 of about 3,071,965 (214)

Lay understandings of drug‐gene interactions: The right medication, the right dose, at the right time, but what are the right words?

open access: yesClinical and Translational Science, 2022
As pharmacogenomic (PGx) testing increases in popularity, lay concepts of drug‐gene interactions set the stage for shared decision making in precision medicine.
Karen M. Meagher   +6 more
doaj   +1 more source

TRANSLATIONAL RESEARCH ETHICS

open access: yesSabiad, 2022
The purpose of translational research is to test novel therapeutic strategies and drugs throughout basic and clinical research. The basic concept of translational research is ‘Bench to Bedside’, defining the collaboration between clinicians and basic ...
Ali Yağız Üresin, Şebnem Dönmez
doaj   +1 more source

The full spectrum of ethical issues in dementia research: findings of a systematic qualitative review

open access: yesBMC Medical Ethics, 2021
Background When including participants with dementia in research, various ethical issues arise. At present, there are only a few existing dementia-specific research guidelines (Committee for Medicinal Products for Human Use in Clinical investigation of ...
Tim G. Götzelmann   +2 more
doaj   +1 more source

Ethics in research

open access: yesClinical Nutrition Open Science, 2023
Ethics in research and how it is translated into practice is fundamental to rule out any potential misconduct either with the scientific method or the way results are presented to the world, thus impacting patients outcomes.The last two years of the ...
Maria Isabel Toulson Davisson Correia
doaj   +1 more source

Race in health research: Considerations for researchers and research ethics committees

open access: yesSouth African Journal of Bioethics and Law, 2023
This article provides ethical guidance on using race in health research as a variable or in defining the study population. To this end, a plain, non-exhaustive checklist is provided for researchers and research ethics committees, preceded by a brief ...
W Van Staden   +21 more
doaj   +1 more source

Guiding ethical principles in transplant candidate selection committees: A scoping review protocol.

open access: yesPLoS ONE
ObjectiveThe goal of this scoping review is to examine the published literature regarding ethical principles that guide solid-organ transplant candidate selection committees.
Christopher H Kim   +3 more
doaj   +2 more sources

Qualitative study of comprehension of heritability in genomics studies among the Yoruba in Nigeria

open access: yesBMC Medical Ethics, 2020
Background With growth of genomics research in Africa, concern has arisen about comprehension and adequacy of informed consent given the highly technical terms used in this field.
Rasheed O. Taiwo   +7 more
doaj   +1 more source

Exportation of unethical practices to low and middle income countries in biomedical research

open access: yesRevista de Bioética y Derecho, 2019
Substandard ethical practices in biomedical research have been exported from more developed countries to less developed countries worldwide. The term for this practice is called ethics dumping, which can be described as exporting, in clinical research ...
Germán Novoa-Hecke   +2 more
doaj   +1 more source

A meta-analysis of threats to valid clinical inference in preclinical research of sunitinib

open access: yeseLife, 2015
Poor study methodology leads to biased measurement of treatment effects in preclinical research. We used available sunitinib preclinical studies to evaluate relationships between study design and experimental tumor volume effect sizes.
Valerie C Henderson   +6 more
doaj   +1 more source

Improving the process of research ethics review

open access: yesResearch Integrity and Peer Review, 2017
Background Research Ethics Boards, or Institutional Review Boards, protect the safety and welfare of human research participants. These bodies are responsible for providing an independent evaluation of proposed research studies, ultimately ensuring that ...
Stacey A. Page, Jeffrey Nyeboer
doaj   +1 more source

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