Results 11 to 20 of about 2,946,321 (262)

A meta-analysis of threats to valid clinical inference in preclinical research of sunitinib

eLife, 2015
Poor study methodology leads to biased measurement of treatment effects in preclinical research. We used available sunitinib preclinical studies to evaluate relationships between study design and experimental tumor volume effect sizes.
Valerie C Henderson, Nadine Demko, Amanda Hakala, Nathalie MacKinnon, Carole A Federico, Dean Fergusson, Jonathan Kimmelman   +6 more
doaj   +1 more source

Ethics in research

Indian Journal of Medical Microbiology, 2006
Research in biomedical science in India has undergone a sea change in the recent years. Globalization, free market and easy access to information, have contributed to this change. Research and publications have gained importance now more than ever before.
openaire   +2 more sources

Improving the process of research ethics review

Research Integrity and Peer Review, 2017
Background Research Ethics Boards, or Institutional Review Boards, protect the safety and welfare of human research participants. These bodies are responsible for providing an independent evaluation of proposed research studies, ultimately ensuring that ...
Stacey A. Page, Jeffrey Nyeboer
doaj   +1 more source

RESEARCH ETHICS

Pakistan Armed Forces Medical Journal, 2018
Research is defined as any form of a careful consideration of a study concerning a problem that aims to contribute to a body of knowledge or theory by means of scientific methods.
Brig Khadija Qamar
doaj   +2 more sources

Comités de etica de investigación en humanos: el desafío de su fortalecimiento en Colombia.

Biomédica: revista del Instituto Nacional de Salud, 2006
Introducción. Los comités de ética de investigación en humanos que aplican los estándares internacionales en la evaluación ética de proyectos de investigación son un recurso indispensable para garantizar la integridad ética de la investigación en humanos.
María Consuelo Miranda, Gloria I. Palma, Ernesto Jaramillo   +2 more
doaj   +1 more source

Professional and academic profile of the Brazilian research ethics committees

BMC Medical Ethics, 2022
Background Brazil is among the sixteen countries that conducts the most clinical trials in the world. It has a system to review research ethics with human beings made up by the National Commission on Research Ethics (CONEP) and 779 Research Ethics ...
Eugênio Pacelli de Veras Santos, Iara Coelho Zito Guerriero   +1 more
doaj   +1 more source

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks, Molly Sonenklar, Cerelia Donald, Cecelia Valrie, Wally Smith, India Sisler   +5 more
wiley   +1 more source

Favorable research environment is a key determinant of research integrity according to a ten-country survey across Central and Eastern Europe

Scientific Reports
Our study was designed to investigate research integrity among scientists actively working in biomedicine. Using the unique opportunity of the Alliance for Life Sciences, a networking initiative of leading research institutions and universities in ...
Renata Veselska, Jan Sirucek, Eugenijus Gefenas, Ana Borovecki, Alliance for Life Focus Group 2: Research Ethics and Research Integrity   +4 more
doaj   +1 more source

Why genomics researchers are sometimes morally required to hunt for secondary findings

BMC Medical Ethics, 2020
Background Genomic research can reveal ‘unsolicited’ or ‘incidental’ findings that are of potential health or reproductive significance to participants.
Julian J. Koplin, Julian Savulescu, Danya F. Vears   +2 more
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source