Results 161 to 170 of about 3,121,640 (312)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

මාර්ගගත ක්‍රමවල සුරක්ෂිතභාවය පිළිබඳ පනත් කෙටුම්පත පාර්ලිමේන්තුවේදී සම්මත වීම සිංහල සහ ඉංග්‍රීසි පුවත්පත් මුල්පිටු සිරස්තල දැක්වූ ආකාරය [PDF]

This entry includes a write-up and an infographic (both in Sinhala).On January 25, 2024, Ethics Eye posted a post showing the front page headlines from Sinhala and English newspapers about the passing of the Online Safety Bill.
Ethics Eye
core  

Research ethics, consent and publication

Heliyon, 2023
Marc Cornock, Margaret Rees
doaj   +1 more source

Ethics of research methodology requires a methodology of research ethics [PDF]

Journal of Clinical Epidemiology, 2018
Knottnerus, J. Andre, Tugwell, Peter
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

ETHICS IN ECONOMIC FIELD RESEARCH or SHORT STORIES OF DEPENDENCY [PDF]

The paper is an attempt to use the idea of reflexivity in order to organise and set �ready for answers� the ethical issues which have arisen at the very beginning of the field research (on a topic in the economics area) and ...
Irene Sotiropoulou
core  

Ethics and Anthropology: A commentary on Andrea Quadrelli’s article “The ethical exercise in dispute”

Salud Colectiva, 2022
Oriol Romaní
doaj   +1 more source

Establishing a peer advisory board in a mental health ethics research group - challenges, benefits, facilitators and lessons learned. [PDF]

Front Psychiatry
Faissner M, Braun E, Efkemann SA, Gaillard AS, Haferkemper I, Hempeler C, Heuer I, Lux U, Potthoff S, Scholten M, Spiegel S, Stefaniak C, Thesing M, Werning A, Gather J.   +14 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source