Results 11 to 20 of about 3,110,108 (316)

A meta-analysis of threats to valid clinical inference in preclinical research of sunitinib

eLife, 2015
Poor study methodology leads to biased measurement of treatment effects in preclinical research. We used available sunitinib preclinical studies to evaluate relationships between study design and experimental tumor volume effect sizes.
Valerie C Henderson, Nadine Demko, Amanda Hakala, Nathalie MacKinnon, Carole A Federico, Dean Fergusson, Jonathan Kimmelman   +6 more
doaj   +1 more source

Challenges to patient centredness – a comparison of patient and doctor experiences from primary care

BMC Family Practice, 2019
Background We designed this observational study to investigate the level of patients’ and doctors’ ratings of patient-centred aspects of the primary care consultation. Methods Questionnaire study with patients and doctors.
Helene Bodegård, Gert Helgesson, Niklas Juth, Daniel Olsson, Niels Lynøe   +4 more
doaj   +1 more source

Individual notions of fair data sharing from the perspectives of Swiss stakeholders

BMC Health Services Research, 2021
Background The meaningful sharing of health data between different stakeholders is central to the advancement of science and to improve care offered to individual patients.
Lester Darryl Geneviève, Andrea Martani, Bernice Simone Elger, Tenzin Wangmo   +3 more
doaj   +1 more source

Factors associated with post-acute discharge location after hospital stay: a cross-sectional study from a Swiss hospital

BMC Health Services Research, 2019
Background In 2012, Switzerland introduced the diagnosis-related group hospital payment system. Fearing that vulnerable patients may be discharged early, Acute and Transitional Care (ATC) was introduced to address the nursing care of patients who no ...
Bettina M. Zimmermann, Insa Koné, Michael Rost, Agnes Leu, Tenzin Wangmo, Bernice S. Elger   +5 more
doaj   +1 more source

Acute and transitional care or rehabilitation? Retrospective analysis of discharge planning from a municipal hospital in Switzerland

BMC Health Services Research, 2020
Background Due to rising health care costs, in 2012 Switzerland introduced SwissDRG, a reimbursement system for hospitals based on lump sum per case. To circumvent possible negative consequences like reduction in length of stay, acute and transitional ...
Lara Kollbrunner, Michael Rost, Insa Koné, Bettina Zimmermann, Yvonne Padrutt, Tenzin Wangmo, Bernice Elger   +6 more
doaj   +1 more source

Race in health research: Considerations for researchers and research ethics committees

South African Journal of Bioethics and Law, 2023
This article provides ethical guidance on using race in health research as a variable or in defining the study population. To this end, a plain, non-exhaustive checklist is provided for researchers and research ethics committees, preceded by a brief ...
W Van Staden, A Nienaber, T Rossouw, A Turner, C Filmalter, A E Mercier, J G Nel, B Bapela, M M Beetge, R Blumenthal, C D V Castelyn, T W de Witt, A G Dlagnekova, C Kotze, J S Mangwane, L Napoles, R Sommers, L Sykes, W B van Zyl, M Venter, A Uys, N Warren   +21 more
doaj   +1 more source

ethical review and ethical behaviour [PDF]

BMJ, 2005
Wade's main concern is that the distinction between audit and research is arbitrary and often means that attention is not paid to what is really ethically important in many aspects of medicine.1 We agree that the distinction between audit and research is difficult to sustain.
John, McMillan, Mark, Sheehan
openaire   +2 more sources

Qualitative study of comprehension of heritability in genomics studies among the Yoruba in Nigeria

BMC Medical Ethics, 2020
Background With growth of genomics research in Africa, concern has arisen about comprehension and adequacy of informed consent given the highly technical terms used in this field.
Rasheed O. Taiwo, John Ipadeola, Temilola Yusuf, Faith Fagbohunlu, Gbemisola Jenfa, Sally N. Adebamowo, Clement A. Adebamowo, the Indigene Study as part of the H3Africa Consortium   +7 more
doaj   +1 more source

The full spectrum of ethical issues in pediatric genome-wide sequencing: a systematic qualitative review

BMC Pediatrics, 2021
Background The use of genome-wide sequencing in pediatric medicine and research is growing exponentially. While this has many potential benefits, the normative and empirical literature has highlighted various ethical issues. There have not been, however,
Johanna Eichinger, Bernice S. Elger, Insa Koné, Isabel Filges, David Shaw, Bettina Zimmermann, Stuart McLennan   +6 more
doaj   +1 more source

A palliative care approach in psychiatry: clinical implications

BMC Medical Ethics, 2020
Background Traditionally, palliative care has focused on patients suffering from life-threatening somatic diseases such as cancer or progressive neurological disorders.
Mattias Strand, Manne Sjöstrand, Anna Lindblad   +2 more
doaj   +1 more source