Results 21 to 30 of about 2,457,030 (220)
Ethics and OR: Operationalising Discourse Ethics [PDF]
Operational researchers help managers decide what they ought to do and yet this is generally evaluated in terms of efficiency or effectiveness, not ethicality.
Pfeffermann, Danny, Sverchkov, Michail
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Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink+6 more
wiley +1 more source
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen+13 more
wiley +1 more source
Q-SEA - a tool for quality assessment of ethics analyses conducted as part of health technology assessments [PDF]
Introduction: Assessment of ethics issues is an important part of health technology assessments (HTA). However, in terms of existence of quality assessment tools, ethics for HTA is methodologically under-developed in comparison to other areas of HTA ...
Bakke Lysdahl, Kristin+5 more
core +3 more sources
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha+6 more
wiley +1 more source
For SSHRC funded projects, the Applicant, now Principal Investigator (PI), has responsibility for the direction of the project and all financial expenditures.
Canadian Business Ethics Research Network (CBERN)
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NEPOTISM PROHIBITIONS - SUPERVISORY CONFLICTS OF INTEREST CERTIFICATION FORM [PDF]
NEPOTISM PROHIBITIONS - SUPERVISORY CONFLICTS OF INTEREST CERTIFICATION FORM Pursuant to N.J.S.A.52:13D-21.2(c), no State officer or employee may supervise or exercise authority over the personnel actions of a relative* of the State officer or employee.
Ethics Office
core +1 more source
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini+11 more
wiley +1 more source
CBERN - The First Six Years: Challenges and Achievements [PDF]
CBERN was created in 2006. Its mandate was to create a network able to address critically, persuasively and visibly the foundational role of ethics in business and economic development. The task facing the network was significant. The field was fractured
Canadian Business Ethics Research Network (CBERN)
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