Results 51 to 60 of about 5,749,433 (313)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Integrating ethics in AI development: a qualitative study

open access: yesBMC Medical Ethics
Background While the theoretical benefits and harms of Artificial Intelligence (AI) have been widely discussed in academic literature, empirical evidence remains elusive regarding the practical ethical challenges of developing AI for healthcare. Bridging
Laura Arbelaez Ossa   +5 more
doaj   +1 more source

A qualitative study on existential suffering and assisted suicide in Switzerland

open access: yesBMC Medical Ethics, 2019
Background In Switzerland, people can be granted access to assisted suicide (AS) on condition that the person whose wish is to die performs the fatal act, that he has his decisional capacity and that the assisting person’s conduct is not selfishly ...
Marie-Estelle Gaignard, Samia Hurst
doaj   +1 more source

Mapping ethical issues in the use of smart home health technologies to care for older persons: a systematic review

open access: yesBMC Medical Ethics, 2023
Background The worldwide increase in older persons demands technological solutions to combat the shortage of caregiving and to enable aging in place.
Nadine Andrea Felber   +4 more
doaj   +1 more source

Philosophical Legal Ethics: An Affectionate History [PDF]

open access: yes, 2017
The modern subject of theoretical legal ethics began in the 1970s. This brief history distinguishes two waves of theoretical writing on legal ethics.
Luban, David, Wendel, W. Bradley
core   +2 more sources

“Ethics Ready”? Governing Research Through Informed Consent Procedures [PDF]

open access: gold, 2023
Florence Caeymaex   +3 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

(WP 2018-03) Comment on White on the Relationship between Economics and Ethics [PDF]

open access: yes, 2018
This short comment on Mark White’s comment on the relationship of economics and ethics focuses on the nature of economics and ethics as an emergent field of investigation.
Davis, John B.
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Why should HCWs receive priority access to vaccines in a pandemic?

open access: yesBMC Medical Ethics, 2021
Background Viral pandemics present a range of ethical challenges for policy makers, not the least among which are difficult decisions about how to allocate scarce healthcare resources.
Xavier Symons   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy