Results 51 to 60 of about 3,110,108 (316)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Mapping ethical issues in the use of smart home health technologies to care for older persons: a systematic review

BMC Medical Ethics, 2023
Background The worldwide increase in older persons demands technological solutions to combat the shortage of caregiving and to enable aging in place.
Nadine Andrea Felber, Yi Jiao (Angelina) Tian, Félix Pageau, Bernice Simone Elger, Tenzin Wangmo   +4 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Forum: Interpretation of the Canadian Association of Social Workers’ Code of Ethics as Penguin Comic [PDF]

, 2023
Jenna Horback
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Medical Ethics as Professional Ethics [PDF]

The Korean Journal of Gastroenterology, 2012
Contemporary medical ethics is far from the traditional concept of "In-Sul (benevolent art)" or "Yul-Li (倫, ethics), which emphasizes so much the personality or the character of a doctor. Nowadays, medical ethics should be considered as "professional ethics" which regulates the acts and medical practices of ordinary doctors in their daily practice. The
openaire   +2 more sources

Promoting xenomorphic patient-facing AIs: The case against anthropomorphism in medical AIs

npj Digital Medicine
The rapid emergence of patient-facing medical artificial intelligence (MAI) raises pressing questions about its design and impact on healthcare.
Stephen R. Milford, Emma Herger, Johanna Eichinger, Bernice S. Elger   +3 more
doaj   +1 more source

Digital pills: a scoping review of the empirical literature and analysis of the ethical aspects

BMC Medical Ethics, 2020
Background Digital Pills (DP) are an innovative drug-device technology that permits to combine traditional medications with a monitoring system that automatically records data about medication adherence as well as patients’ physiological data.
Andrea Martani, Lester Darryl Geneviève, Christopher Poppe, Carlo Casonato, Tenzin Wangmo   +4 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Ethics and Ethical Problem Solving

, 2022
In this chapter we define behavioral systems and behavioral systems analysis with examples of contexts where behavioral systems may be used to fulfill ethical obligations of protecting consumers and providing high quality care. Specifically, we describe a systems approach to incorporate consumer choice into treatment decisions, monitoring adverse ...
Matthew Thornton Brodhead, Noel Oteto
openaire   +1 more source