Results 51 to 60 of about 6,158,971 (399)
, 2008 For SSHRC funded projects, the Applicant, now Principal Investigator (PI), has responsibility for the direction of the project and all financial expenditures.
Canadian Business Ethics Research Network (CBERN)
core
Values ethics and legal ethics: the QLD and LETR recommendations 6, 7, 10, and 11 [PDF]
, 2014 The LETR Report recommended increased attention to ethics and values and to critical thinking. These aims could be achieved jointly through teaching ethical thinking: not as theory but as part of developing the capacity for ethical conduct.
Ferris, G
core +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
BMC Medical Ethics, 2020 Background Evaluation of decision-making capacity to consent to medical treatment has proved to be difficult in patients with dementia. Studies showed that physicians are often insufficiently trained in the evaluation of decision-making capacity. In this
Christopher Poppe +3 more
doaj +1 more source
CBERN - The First Six Years: Challenges and Achievements [PDF]
, 2012 CBERN was created in 2006. Its mandate was to create a network able to address critically, persuasively and visibly the foundational role of ethics in business and economic development. The task facing the network was significant. The field was fractured
Canadian Business Ethics Research Network (CBERN)
core
The ethics of sociocultural risk research [PDF]
, 2001 In socio-cultural risk research, an epistemological tension often follows if real hazards in the world are juxtaposed against the essentially socially constructed nature of all risk.
Sarre, S +4 more
core +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
BMC Geriatrics, 2018 Background Close to half of all deaths in Norway occur in nursing homes, which signals a need for good communication on end-of-life care. Advance care planning (ACP) is one means to that end, but in Norwegian nursing homes, ACP is not common.
Trygve Johannes Lereim Sævareid +5 more
doaj +1 more source
Dangerous ontologies: the ethos of survival and ethical theorising in international relations [PDF]
, 2002 The article responds to a recent call for a more systematic interrogation of the persistence of the dichotomous relation between ethics and International Relations.
Odysseos, Louiza
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source