Results 101 to 110 of about 213,995 (337)
Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann +11 more
wiley +1 more source
Navigating the challenges of initiating pediatric device trials – a case study
Introduction: Pediatric medical devices lag behind adult devices due to economic barriers, smaller patient populations, changing anatomy and physiology of patients, regulatory hurdles, and especially difficulties in executing clinical trials.
R. Brandon Hunter +8 more
doaj +1 more source
Neuromodulator Dynamics Underlying Associative Learning in the Ventral Striatum's Olfactory Tubercle
Using fiber photometry and genetically encoded sensors, the dynamic release patterns of four neuromodulators in the olfactory tubercle (OT)—a brain region overlapping with the olfactory cortex and ventral striatum—were systematically monitored in response to external rewards and distinct reward‐associated learning processes.
Maojun Hong +7 more
wiley +1 more source
Lefebvre’s 1970 prophecy of the total urbanisation of society has come true with the expansion of the urban into natural and rural territories. For Lefebvre, the question of nature is closed by its ‘steady, violent death’ (Lefebvre, 2003) and its ...
Hurducaş Iulia
doaj +1 more source
A Climate of Disorder: What to do About the Obstacles to Effective Climate Politics [PDF]
The emphasis on general distributive principles in the climate justice literature has left significant gaps regarding the problem of weak climate governance.
Maltais, Aaron
core
Mediating Multiculturally: Culture and the Ethical Mediator [PDF]
This commentary on mediating multiculturally in a chapter of Mediation Ethics (edited by Ellen Waldman) suggests there are times when mediators should not mediate, because of their own ethical commitments.
Abramson, Harold I +1 more
core +2 more sources
The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan +8 more
wiley +1 more source
Introducing a predictive experiment: Ethics, data and public defence in Chile
This article examines the development of a predictive system intended to forecast favourable trial outcomes within Chile's Public Defender's Office, analysing how ethical principles are negotiated, contested, and transformed throughout its design and ...
Arturo Arriagada, Dusan Cotoras
doaj +1 more source
This article uses the concept of compassionate deception to understand the complexity and duality at stake when health professionals and family members lie when caring for people with dementia.
Sofie Smedegaard Skov +4 more
doaj +1 more source
Introduction This study aims to provide a landscape of the global antiretroviral (ARV) market by analyzing the transactional data on donor‐funded ARV procurement between 2003 and 2015, and the ARV price determinants.
Luis Sagaon‐Teyssier +3 more
doaj +1 more source

