Results 121 to 130 of about 2,047,734 (258)
Electronic informed consent criteria for research ethics review: a scoping review. [PDF]
BMC Med Ethics, 2022 Yusof MYPM, Teo CH, Ng CJ.
europepmc +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Empowering local research ethics review of antibacterial mass administration research. [PDF]
Infect Dis Poverty, 2022 Sewankambo NK, Kutyabami P.
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Multisite Research Ethics Review: Problems and Potential Solutions
BioéthiqueOnline, 2016 Large scale, multisite clinical research trials have been increasing in frequency. As it stands currently, a research project performed at multiple institutions requires ethics review at each institution.
Ferguson, Aidan, Master, Zubin
doaj
Ethics review, reflective equilibrium and reflexivity. [PDF]
Nurs Ethics, 2022 Morton J.
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Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Governance Frameworks for COVID-19 Research Ethics Review and Oversight in Latin America: An Exploratory Study [PDF]
BMC Med Ethics, 2021 Palmero A +3 more
europepmc +2 more sources
Correspondence on “Changes in memory and cognition during the SARS-CoV-2 human challenge study”
EClinicalMedicineRaffaella Ravinetto +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source