Effect of flavonoids identified in grape pomace extract on efflux pump in <i>Staphylococcus aureus</i>. [PDF]
Sanhueza L +6 more
europepmc +1 more source
KU80 suppresses endonuclease G activity to preserve genomic integrity
Under normal conditions, EndoG remains restricted to mitochondria and the genome remains intact. When KU80 is absent, EndoG translocates into the nucleus, where it promotes DNA fragmentation and genomic instability. Thus, this work highlights the importance of KU80 in tightly controlling EndoG localization to preserve genome stability.
Jargalan Batsaikhan +8 more
wiley +1 more source
Photobiomodulation pre-treatment enhances ALA-induced PpIX accumulation and photodynamic therapy response in oral squamous cell carcinoma cells in cell culture. [PDF]
Ferro AP +4 more
europepmc +1 more source
The genes PH0137, PH0138, and PH0140 form a cluster in the genome of Pyrococcus horikoshii. The PH0140 gene encodes a transcription factor identified as a d‐amino acid‐responsive regulatory protein (DARP). In feast mode, l‐Ile‐bound DARP binds to the promoter and represses transcription of PH0137 and PH0138. In famine mode, DARP binds to d‐allo‐Ile and
Ryushi Kawakami +6 more
wiley +1 more source
Adipose-Derived Stem Cells Differentiate Into Insulin-Producing Cells in 2D Culture With Photobiomodulation: A Comparative Analysis of Wavelength and Fluence Parameters. [PDF]
Daramola O, Abrahamse H, Crous A.
europepmc +1 more source
Astrocytic gap junctions formed by connexin43 (Cx43) help maintain brain homeostasis. After mild traumatic brain injury (TBI), total cortical Cx43 increases and redistributes toward a soluble, non‐junctional pool with elevated hemichannel activity and increased phosphorylation at serine 368 (pCx43S368).
Carmen Muñoz‐Ballester +11 more
wiley +1 more source
Enhanced fibrinolytic enzyme production by Oidiodendron maius through green bioprocessing of agro-industrial residue. [PDF]
Sajid H, Iqbal M, Gull-E-Faran.
europepmc +1 more source
ABSTRACT Aim Hypoxic preconditioning of cells holds promise for regenerative therapies, yet identifying effective and safe methods for clinical application remains challenging. We aimed to determine optimal hypoxia‐mimetic small molecules (SMs) that stabilize hypoxia‐inducible factor‐1α (HIF‐1α) and their dosages for hypoxic preconditioning in stem ...
Hong Wang +9 more
wiley +1 more source
Stiff matrix impairs cytotoxic T lymphocyte function at multiple levels. [PDF]
Seyedzadeh MH +9 more
europepmc +1 more source
Bacteriomes, cryptic forms and evolution of a common wireworm pest species, Hypnoidus bicolor
Wireworms are important agricultural pests, including Hypnoidus bicolor in the Canadian Prairies. Parthenogenetic and sexual populations of H. bicolor appear associated with different molecular clades. Bacterial community composition and structure were influenced by developmental stage, sampling location and host genetics.
Ivan Drahun +5 more
wiley +1 more source

