Isolation and subtyping of avian influenza A virus from wild birds in Khartoum, Sudan. [PDF]
Ali WH +10 more
europepmc +1 more source
Mucin Glycoprotein Nanoparticles Enable a Selective Antisense Therapy for Oncogenic MicroRNAs
Mucin glycoproteins are turned into nanoparticles by employing synthetic DNA strands, which have a dual function: they stabilize the nanoparticles and act as binding sites for intracellular miRNA‐21. Thus, upon internalization into tumor cells, these mucin nanoparticles can deplete miRNA‐21 from the cytosol, which induces apoptosis in vitro and in vivo.
Ceren Kimna +9 more
wiley +1 more source
Strain-dependent contribution of the AcrAB-TolC efflux pump to <i>Klebsiella pneumoniae</i> physiology. [PDF]
Bhogal K +6 more
europepmc +1 more source
Hydrogel Embedding of Mesenchymal Stem Cells Supports Extracellular Vesicle Production
This study investigates the effects of 3D culture conditions on extracellular vesicle (EV) production by mesenchymal stem cells (MSCs) in a gelatin‐based hydrogel matrix (GelMA). The EVs from both conditions were found to have similar morphological, molecular, and functional properties, but 3D cultures produced more total EVs per volume.
Rachel K. Moen +5 more
wiley +1 more source
Molecular determinants of substrate specificity in the efflux pump CraA from <i>Acinetobacter baumannii</i>. [PDF]
Foong WE, Xiang X, Pos KM, Tam H-K.
europepmc +1 more source
Thermodynamics of interaction of aromatic ligand with single-stranded DNA: 1H NMR analysis of complex formation between ethidium bromide and non-complementary isomeric deoxytetranucleotides 5'-d(CGAA) and 5'-d(AAGC) [PDF]
A. N. Veselkov +6 more
openalex +1 more source
Improved Messenger RNA Stability and Biocompatibility Through Self‐Gelatinizable Nucleic Acids
ABSTRACT Recent advances in the chemical synthesis and modification of messenger RNA (mRNA) have generated growing interest in mRNA‐based therapeutics. However, the inherent instability of mRNA in vivo and during storage remains a major challenge, requiring the development of safe and effective delivery systems.
Takumi Tanifuji +5 more
wiley +1 more source
ArcA modulates multidrug resistance and compound susceptibility in <i>Klebsiella pneumoniae</i> through ArcB-independent regulation of the SMR efflux pump kpnEF. [PDF]
Fu T +18 more
europepmc +1 more source

