Results 91 to 100 of about 246,567 (336)

The HLA-E Gene encodes two differentially regulated Transcripts and a Cell Surface Protein [PDF]

, 1992
An HLA-E-specific oligonucleotide probe was used to study the expressioonf HLA-E. This probed etects two HLA-E transcripts, 1.8 and 2.7 kb in size, which are present in varying ratios in allt issues and cell lines investigated.
Honka, Thomas, Johnson, Judith P., Person, Susanne, Ulbrecht, Matthias, Weiss, Elisabeth H.   +4 more
core   +1 more source

An Intelligent Magneto‐Mechanical Platform for Cellular Sensing in 3D Microenvironments

Advanced Science, EarlyView.
This study presents MagMI, a pioneering machine intelligence‐driven magneto‐mechanical sensing platform. It utilizes magneto‐mechanical arrays and machine learning to achieve label‐free, real‐time monitoring and classification of cellular proliferation dynamics within 3D microenvironments.
Yue Quan, Yuxin Wang, Sen Ding, Bingpu Zhou, Yinning Zhou   +4 more
wiley   +1 more source

Genetic diversity among viruses associated with sugarcane mosaic disease in Tucumán, Argentina [PDF]

, 2009
Sugarcane leaves with mosaic symptoms were collected in 2006--07 in Tucumán (Argentina) and analyzed by reverse-transcriptase polymerase chain reaction (RT-PCR) restriction fragment length polymorphism (RFLP) and sequencing of a fragment of the Sugarcane
Castagnaro, Atilio Pedro, Cuenya, María Inés, Filippone, María Paula, Garcia, Maria Laura, Perera, María Francisca, Ploper, Leonardo Daniel, Ramallo, C. J.   +6 more
core   +2 more sources

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Neuroprotective Effects of Myricitrin on Cognitive Deficits in Hippacampal Demyelinated Rats

Journal of Mazandaran University of Medical Sciences, 2019
Background and purpose: Multiple sclerosis (MS) as an autoimmune disease is the most common demyelinating inflammatory disease in young people that affects the central nervous system.
Fatemeh SargolzaeeJavan, Mohammad Ali Mirshekar, Mohammadreza Shahraki   +2 more
doaj  

DNA Oxidation Photoinduced by Norharmane Rhenium(I) Polypyridyl Complexes: Effect of the Bidentate N,N′-Ligands on the Damage Profile [PDF]

, 2018
ReI-polypyridyl complexes have interesting and distinctive photochemical and photosensitizing properties. This work describes the capability to induce (or photoinduce) DNA damage of three ReI-complexes with a naturally occurring alkaloid called ...
Ahmad, Balasingham, Balón, Blasius, Boerner, Boiteux, Bonett, Cao, Coggan, Copeland, Crespy, Daley, de Souza, Dhar, Dong, Epe, Epe, Erkkila, Etienne, Feliz, Fernández-Moreira, Friedman, Gasser, Ghesquière, Gonzalez, Gonzalez, Gonzalez, Gonzalez, Gonzalez, Gonzalez, Hayashi, Häring, Kaplanis, Kastl, Kaulage, Knopf, Krokan, Kumar, Kydonaki, Lakowicz, Lee, Leonidova, Lhiaubet-Vallet, Lo, Maisuls, Maisuls, Maisuls, Mari, Marker, Maron, Martí, McKenzie, McKinley, Müller, Ng, Niesel, Paul, Pohl, Pyle, Ragone, Rasse-Suriani, Ruiz, Ruiz, Ruiz, Salditt, Schatzschneider, Schmidt, Schutte, Schäfer, Shahabadi, Smith, Song, Stemp, Stoeffler, Sun, Taira, Thornton, Vignoni, Wilson, Wolfe, Zeglis, Ziessel, Zobi   +82 more
core   +1 more source

Co‐Opting MBNL‐Dependent Alternative Splicing Cassette Exons to Control Gene Therapy in Myotonic Dystrophy

Annals of Neurology, EarlyView.
Objective Myotonic dystrophy type 1 (DM1) is a highly variable, multisystemic genetic disorder caused by a CTG repeat expansion in the 3′ untranslated region of DMPK. Toxicity is exerted by repeat‐containing DMPK transcripts that sequester muscleblind‐like (MBNL) proteins and lead to deleterious yet predictable changes in alternative splicing.
Samuel T. Carrell, Ellie M. Carrell, Ryan Giovenco, Beverly L. Davidson   +3 more
wiley   +1 more source

Protocol for high-sensitivity/long linear-range spectrofluorimetric DNA quantification using ethidium bromide

BioTechniques, 2007
Ethidium bromide (EtBr) is the most widely used fluorescent dye in nucleic acid gel electrophoresis since decades. However, it has been essentially forgotten in DNA quantification by spectrofluorimetry.
Veronica Bonasera, Saverio Alberti, Andrea Sacchetti   +2 more
doaj   +1 more source

A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern [PDF]

, 2003
The var multicopy gene family encodes Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) variant antigens, which, through their ability to adhere to a variety of host receptors, are thought to be important virulence factors.
Sue A. Kyes, Zoe Christodoulou, Ahmed Raza, Paul Horrocks, Robert Pinches, J. Alexandra Rowe, Chris I. Newbold, Aguiar, Baruch, Beeson, Berendt, Bonnefoy, Brabin, Buffet, Bull, Chen, Chen, Church, Duffy, Fidock, Fowler, Freitas-Junior, Fried, Fried, Fried, Gardner, Gardner, Goda, Kyes, Kyes, Lambros, Lekana Douki, Marsh, Newbold, Pouvelle, Reeder, Ricke, Roberts, Robson, Rowe, Rowe, Rubio, Salanti, Scherf, Smith, Smith, Smith, Su, Taylor, Trager, Vazquez-Macias, Voss   +51 more
core   +1 more source

Improved Messenger RNA Stability and Biocompatibility Through Self‐Gelatinizable Nucleic Acids

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Recent advances in the chemical synthesis and modification of messenger RNA (mRNA) have generated growing interest in mRNA‐based therapeutics. However, the inherent instability of mRNA in vivo and during storage remains a major challenge, requiring the development of safe and effective delivery systems.
Takumi Tanifuji, Kosuke Kusamori, Chihiro Tanaka, Hideki Sakai, Shoko Itakura, Makiya Nishikawa   +5 more
wiley   +1 more source