Investigation of Gel Electrophoresis Stains
Gel electrophoresis is essential in molecular biology and biochemistry for separating and analyzing DNA, RNA, and proteins. UV sensitivity and compatibility have led to the use of ethidium bromide stains.
ibrahim ramzi hadi +4 more
doaj +1 more source
Fluorometric determination of ethidium bromide efflux kinetics in
Background Efflux pump activity has been associated with multidrug resistance phenotypes in bacteria, compromising the effectiveness of antimicrobial therapy.
Monteiro Gabriel A +9 more
doaj +1 more source
Application of the SwitchSense Technique for the Study of Small Molecules' (Ethidium Bromide and Selected Sulfonamide Derivatives) Affinity to DNA in Real Time. [PDF]
Ramotowska S +4 more
europepmc +1 more source
ABSTRACT Antibiotic resistance poses a serious challenge to public health, particularly in the case of Staphylococcus aureus, a Gram‐positive bacterium that employs multiple resistance mechanisms, including efflux pumps such as NorA, which extrude antimicrobial compounds from the cell and reduce antibiotic efficacy. Therefore, the search for substances
Camila Aparecida Pereira da Silva +10 more
wiley +1 more source
The Identification of Ethidium Bromide-Degrading Bacteria from Laboratory Gel Electrophoresis Waste. [PDF]
Gandhi VP, Kesari KK, Kumar A.
europepmc +1 more source
Specific berenil–DNA interactions: an approach for separation of plasmid isoforms by pseudo–affinity chromatography [PDF]
Small molecules, like some antibiotics and anticancer agents that bind DNA with high specificity can represent a relevant alternative as ligands in affinity processes for plasmid DNA (pDNA) purification.
Almeida, P. +4 more
core +1 more source
Depletion of mtDNA with Ethidium Bromide v1
William Hancock‐Cerutti +1 more
openalex +1 more source
Research Progress of Polyoxometalate‐Integrated Frameworks: Syntheses, Properties, and Applications
This review systematically summarizes the integration of polyoxometalates with covalent organic frameworks, metal‐organic frameworks, hydrogen‐bonded organic frameworks, and emerging porous hosts. It highlights synergistic effects, synthesis strategies, and applications in catalysis, energy storage, sensing, and biomedicine, while addressing current ...
De‐Yin Wang +6 more
wiley +1 more source
Independence from kinetoplast DNA maintenance and expression is associated with multi-drug resistance in Trypanosoma brucei in vitro [PDF]
It is well known that several antitrypanosomatid drugs accumulate in the parasite's mitochondrion, where they often bind to the organellar DNA, the kinetoplast.
A. Schnaufer +32 more
core +1 more source
5‐Substituted 2‐(naphthalen‐2‐yl)‐4H‐chromen‐4‐ones are reported as a novel class of highly potent and selective triplex DNA ligands. These ligands induce triplex formation at submicromolar concentrations and inhibit enzymatic activity via ligand‐mediated triplex formation.
Nghia Tran +4 more
wiley +1 more source

