Results 21 to 30 of about 153,070 (262)

Micro-volume couette flow sample orientation for absorbance and fluorescence linear dichroism [PDF]

, 2004
Linear dichroism (LD) can be used to study the alignment of absorbing chromophores within long molecules. In particular, Couette flow LD has been used to good effect in probing ligand binding to DNA and to fibrous proteins.
Marrington, Rachel, Halsall, DJ, Marrington, R, Rodger, A, Dafforn, Timothy R., Rodger, Alison, Dafforn, Timothy, Dafforn, Tim, Halsall, David J.   +8 more
core   +1 more source

Compounds A-I were tested for DNA intercalation in an ethidium bromide exclusion assay.

, 2022
Each putative ApiAP2 competitor compound was added into a mixture containing double stranded DNA and ethidium bromide. The positive control DNA major groove intercalator DRAQ5 knocks down ethidium bromide fluorescence nearly completely relative to the ...
Charisse Flerida A. Pasaje (13949382), Jacquin C. Niles (304325), Kathryn Shaw-Saliba (3146649), Timothy James Russell (13949370), Irene Kouskoumvekaki (87402), C. Denise Okafor (5727909), Namita Dube (7138676), Francisco-Javier Gamo (181360), Valerie M. Crowley (7331483), Marcelo Jacobs-Lorena (133905), Erandi K. De Silva (13949373), Gabrielle Josling (13949379), Gianni Panagiotou (87405), Manuel Llinás (14834)   +13 more
core   +1 more source

Fluorescence microscopy methods for the determination of somatic cell count in raw cow's milk

Veterinární Medicína, 2016
The direct fluorescence microscopy method with ethidium bromide staining can be used for somatic cell counting in raw cow's milk. However, this method has some limitations that may influence the results of the analysis.
P. Zajac, S. Zubricka, J. Capla, L. Zelenakova   +3 more
doaj   +1 more source

Caffeine-induced release of small molecules from DNA nanostructures

iScience, 2023
Summary: Several planar aromatic molecules are known to intercalate between base pairs of double-stranded DNA. This mode of interaction has been used to stain DNA as well as to load drug molecules onto DNA-based nanostructures.
Bharath Raj Madhanagopal, Sabrina Chen, Ché-Doni Platt, Arun Richard Chandrasekaran   +3 more
doaj   +1 more source

The effect of intrahippocampal injection of estradiol on spatial memory in male rats during multiple sclerosis disease [PDF]

Journal of Advanced Biomedical Sciences, 2014
Background & Objective: Multiple sclerosis (MS) is a demyelinating disease of central nervous system, which is approximately two to three times more common in women than men. It was suggested that sexual hormones affect MS disease.
Vahideh Zarrin, Homeyra Hatami, Alireza Ali Hemmati   +2 more
doaj   +2 more sources

Synthesis and Neuropharmacological Evaluation of Some Novel Quinoxaline 2, 3-Dione Derivatives

The Scientific World Journal, 2012
Quinoxaline-2, 3-dione obtained from cyclocondensation reaction of o-phenylene diamine with oxalic acid was reacted with three different ketones and formaldehyde to give the corresponding Mannich bases in satisfactory yield.
Selvaraj Jubie, Rajamanickam Gayathri, Rajagopal Kalirajan   +2 more
doaj   +1 more source

Quantification of viable Legionella pneumophila cells using propidium monoazide combined with quantitative PCR. [PDF]

, 2011
One of the greatest challenges of implementing fast molecular detection methods as part of Legionella surveillance systems is to limit detection to live cells. In this work, a protocol for sample treatment with propidium monoazide (PMA) in combination
Soria-Soria, Elena, Lorena Martínez, Vicente Catalán, Raquel Múrtula, Múrtula, Raquel, Elena Soria-Soria, Nocker, Andreas, M. Adela Yáñez, Yáñez, M. Adela, Martínez, Lorena, Catalán, Vicente, Andreas Nocker   +11 more
core   +1 more source

Ethidium bromide binding to DNA cryogels

Reactive and Functional Polymers, 2013
Abstract The interaction of the classical intercalator ethidium bromide (EtBr) with the double helical network strands of DNA cryogels was investigated. The cryogels were prepared starting from aqueous solutions of DNA (about 2000 base pairs long) at −18 °C using 1,4-butanediol diglycidyl ether crosslinker under various reaction conditions.
Karacan, Pinar, Okay, Oguz
openaire   +2 more sources

Effects of Deletion of the Connexin 32 gene on pro and Anti-inflammatories Aspects in the Ethidium Bromide Toxic Demyelination Model

Brazilian Journal of Veterinary Pathology, 2012
Gap junctions are cellular structures that allow transit of molecules between cells, allowing intercellular signaling and transportation. They are formed by proteins denominated connexins and represent key structures in highly complex and integrated ...
Fernando Y. M. Hosomi, Luciano Fernandes Sousa, Adriano T. Ramos, Paulo C. Maiorka   +3 more
doaj   +1 more source

Mitochondria‐Damaging Self‐Reporting Probe for Cancer Therapy

Angewandte Chemie, EarlyView.
We developed a class of self‐reporting cationic chemotherapeutic probes that selectively induce mitochondrial damage and apoptosis in cancer cells. Their unique mitochondria‐to‐nucleus fluorescence migration enables real‐time visualization of the therapeutic process. ABSTRACT Mitochondrial damage induced by chemotherapeutic agents through disruption of
Hai Xu, Yura Lee, Sanghee Yoon, Yun Wang, Yejin Cho, Seongyu Choi, Lu Lu, Hua Zhang, Sun Choi, Ki Taek Nam, Juyoung Yoon   +10 more
wiley   +2 more sources