Results 91 to 100 of about 153,070 (262)

Metabarcoding of Pollen Carried by Syrphids Reveals Novel Plant–Pollinator Interactions in a Protected Natural Area and Agricultural Sites

Entomologia Experimentalis et Applicata, EarlyView.
Using DNA metabarcoding, this study investigates pollen transported by syrphids (Syrphidae) in the Dolomiti Bellunesi National Park and agricultural sites in Northern Italy. The analysis reveals a high diversity of visited plant taxa, including previously undocumented plant–pollinator interactions.
Serena Magagnoli, Daniele Sommaggio, Claudio Ratti, Riccardo Baroncelli, Andrea Menicucci, Enrico Vettorazzo, Giovanni Burgio   +6 more
wiley   +1 more source

Applying molecular dynamics simulations to validate OCT1 substrates uncovers vitamin K1 as a high-affinity ligand

Frontiers in Pharmacology
OCT1 is a hepatic membrane uptake transporter of clinical importance in drug metabolism and pharmacokinetics. OCT1 exhibits broad substrate specificity, mediating uptake of diverse compounds, including the neurotransmitter serotonin and the antidiabetic ...
Elham Omer Mahgoub, Reem Ali, Ayman Samara, Dindial Ramotar   +3 more
doaj   +1 more source

Fluorometric determination of ethidium bromide efflux kinetics in Escherichia coli

Journal of Biological Engineering, 2009
Background Efflux pump activity has been associated with multidrug resistance phenotypes in bacteria, compromising the effectiveness of antimicrobial therapy.
Monteiro Gabriel A, de Carvalho Carla CCR, Fernandes Pedro, Martins Marta, Couto Isabel, Rodrigues Liliana, Paixão Laura, Sansonetty Filipe, Amaral Leonard, Viveiros Miguel   +9 more
doaj   +1 more source

Variability in intracellular localization of D‐amino acid oxidase in choroid plexus epithelial cells

The FEBS Journal, EarlyView.
D‐amino acid oxidase (DAO) in choroid plexus epithelial cells (CPECs) shows vesicle‐like localization by histological and super‐resolution analyses. DAO colocalizes with peroxisomal, Golgi, endosomal, lysosomal, autophagosomal, and exosomal markers, indicating diverse subcellular distribution. This suggests DAO is transported within CPECs to metabolize
Koji Ono, Yuji Shishido, Toshiyuki Yamagishi, Kiyoshi Fukui   +3 more
wiley   +1 more source

A cryptic targeting signal creates a mitochondrial FEN1 isoform with tailed R-Loop binding properties.

PLoS ONE, 2013
A growing number of DNA transacting proteins is found in the nucleus and in mitochondria, including the DNA repair and replication protein Flap endonuclease 1, FEN1. Here we show a truncated FEN1 isoform is generated by alternative translation initiation,
Lawrence Kazak, Aurelio Reyes, Jiuya He, Stuart R Wood, Gloria Brea-Calvo, Torgeir T Holen, Ian J Holt   +6 more
doaj   +1 more source

Significance of Fluorescent Spectroscopy in Screening Oral Potentially Malignant Disorders and Oral Cancer by Characterization of Salivary DNA Using Ethidium Bromide-A Comparative Study. [PDF]

South Asian J Cancer, 2023
Jayachnadran S, Prakasarao A, Ramamoorthy S, Manoharan Y.   +3 more
europepmc   +1 more source

Research Notes: Induction of sterility in soybeans with ethidium bromide

, 1977
Ethidium bromide (EB), an acridine compound which binds to nucleic acids, has been used as a mutagen in peanuts by Levy and Ashri (1975). Burton and Hanna (1976) induced cytoplasmic male sterile mutations in peari millet with EB and suggested that EB as ...
Burton, J.
core  

KU80 suppresses endonuclease G activity to preserve genomic integrity

The FEBS Journal, EarlyView.
Under normal conditions, EndoG remains restricted to mitochondria and the genome remains intact. When KU80 is absent, EndoG translocates into the nucleus, where it promotes DNA fragmentation and genomic instability. Thus, this work highlights the importance of KU80 in tightly controlling EndoG localization to preserve genome stability.
Jargalan Batsaikhan, Kwang‐Hyun Park, Hae Ryung Chang, Eunyoung Jung, Myung‐Jin Kim, Jeeyoon Kang, Hyunjo Shim, Eui‐Jeon Woo, Yonghwan Kim   +8 more
wiley   +1 more source

Bacillus cereus efflux protein BC3310 - a multidrug transporter of the unknown major facilitator family, UMF-2

Frontiers in Microbiology, 2015
Phylogenetic classification divides the major facilitator superfamily (MFS) into 82 families, including 25 families that are comprised of transporters with no characterized functions.
Jasmin K Kroeger, Karl eHassan, Aniko eVörös, Roger eSimm, Roger eSimm, Massoud eSaidijam, Massoud eSaidijam, Kim E Bettaney, Andreas eBechthold, Ian T Paulsen, Peter eHenderson, Anne-Brit eKolstø   +11 more
doaj   +1 more source

Forskolin, an Adenylcyclase/cAMP/CREB Signaling Activator Restoring Myelin-Associated Oligodendrocyte Destruction in Experimental Ethidium Bromide Model of Multiple Sclerosis. [PDF]

Cells, 2022
Kapoor T, Mehan S, Suri M, Sharma N, Kumar N, Narula AS, Alshammari A, Alasmari AF, Alharbi M, Assiri MA, Kalfin R.   +10 more
europepmc   +1 more source