Results 141 to 150 of about 239,329 (263)

Polyhydroxybutyrate (PHB) From Biofloc Systems Enhances the Growth and Immune Performance of Genetically Improved Farmed Tilapia

Aquaculture, Fish and Fisheries, Volume 6, Issue 2, April 2026.
ABSTRACT This study characterised polyhydroxybutyrate (PHB)‐producing bacteria from the culture water of genetically improved farmed tilapia (GIFT) in biofloc ponds and investigated the influence of PHB on the growth and immune performance of GIFT. Out of 40 bacterial isolates, Bacillus infantis, Exiguobacterium profundum, Bacillus subtilis, Bacillus ...
Menaga Meenakshisundaram, Jimmy B. Mboya, Felix Sugantham   +2 more
wiley   +1 more source

Improved Messenger RNA Stability and Biocompatibility Through Self‐Gelatinizable Nucleic Acids

Biotechnology and Bioengineering, Volume 123, Issue 4, Page 1077-1086, April 2026.
ABSTRACT Recent advances in the chemical synthesis and modification of messenger RNA (mRNA) have generated growing interest in mRNA‐based therapeutics. However, the inherent instability of mRNA in vivo and during storage remains a major challenge, requiring the development of safe and effective delivery systems.
Takumi Tanifuji, Kosuke Kusamori, Chihiro Tanaka, Hideki Sakai, Shoko Itakura, Makiya Nishikawa   +5 more
wiley   +1 more source

Generation of a Novel Col8a2P2A‐CreERT2 Mouse Line Enables Targeted Genetic Manipulation of Corneal Endothelial Cells and Modeling of Endothelial Decompensation

genesis, Volume 64, Issue 2, April 2026.
ABSTRACT The corneal endothelium is a monolayer of specialized cells that maintains stromal deturgescence and transparency, functions essential for vision. Despite its clinical importance, the developmental origins and homeostatic programs of the endothelium remain poorly understood, in part due to the lack of a lineage‐specific genetic driver.
Yong Yuan, Josiah Holt, Samuel Lorry, Yen‐Chiao Wang, Yueh‐Chiang Hu, Zhixing Ma, Adam Kaufman, Winston Kao, Diego G. Ogando, Chia‐Yang Liu   +9 more
wiley   +1 more source

Comparison of Pomological and iPBS Marker‐Based Genetic Characteristics of Some Jackfruit Types From Bangladesh: Identification of Promising Fruit Types

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
In this research work, we categorized 73 accessions of jackfruit genotypes into four major fruit types named “Gala”, “Khaja”, “Rosha”, and “Improved Gala” based on 18 fruit morphometric traits randomly selected from around 500 trees of the DIU campus.
Mohammad A. Rahim, Nusrat Sultana, A. T. M. Majharul Mannan, Most. Efat Jahan Monju, Samsun Naher Oshi, Md. Shoaib Arifin, Uswatun Hasana Hashi   +6 more
wiley   +1 more source

Cassava Endophytic Bacteriome as Potential Biocontrol Agents Against Three Crop Phytopathogenic Fungi

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
Eighty‐four endophytic bacteria from cassava were assessed for antagonistic activity against phytopathogens Colletotrichum siamense, Colletotrichum sublineola and Phytophthora infestans infecting cassava, sorghum and potato, respectively. Fourteen endophytic bacteria exhibited antifungal activity against the three phytopathogens, of which four ...
Roselyne Nyawir Owino, Edward K. Nguu, George O. Obiero, Evans N. Nyaboga   +3 more
wiley   +1 more source

A Simple and Label‐Free Gold Nanoparticle Assay and Duplex PCR for Rapid Detection of Klebsiella pneumoniae K2

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
A rapid, cost‐effective dual‐detection strategy for Klebsiella pneumoniae K2 was developed by combining a label‐free AuNP colorimetric assay (LOD: 1.56 ng/μL, 60 min) with duplex PCR targeting K2A and orf10 genes (LOD: 1 pg/μL). This approach enables rapid screening with accurate genetic validation for point‐of‐care diagnostics in resource‐limited ...
Sepideh Ahmadi, Fatemeh Haddadi, Hossein Kamaladini   +2 more
wiley   +1 more source

Moderating effects of crocin on some stress oxidative markers in rat brain following demyelination with ethidium bromide. [PDF]

Heliyon, 2019
Fathimoghadam H, Farbod Y, Ghadiri A, Fatemi R.   +3 more
europepmc   +1 more source

Dual Targeting of DNA and EGFR by ZYH005 Induces DNA Damage and Mitotic Catastrophe in Glioblastoma

MedComm, Volume 7, Issue 4, April 2026.
ZYH005 exerts potent anti‐glioblastoma activity through a dual mechanism: intercalation‐mediated DNA damage and targeted inhibition of EGFR, leading to cell cycle arrest and mitotic catastrophe. ABSTRACT Glioblastoma multiforme (GBM) is an aggressive, therapy‐resistant brain tumor with limited treatment options.
Jianzheng Huang, Zijun Zhang, Yang Xiao, Ziming Zhao, Zengwei Luo, Junjun Liu, Suitian Lai, Chao Song, Shouchang Feng, Suojun Zhang, Xingjiang Yu, Qingyi Tong, Yonghui Zhang   +12 more
wiley   +1 more source

The VirAB-VirSR-AnrAB Multicomponent System Is Involved in Resistance of Listeria monocytogenes EGD-e to Cephalosporins, Bacitracin, Nisin, Benzalkonium Chloride, and Ethidium Bromide. [PDF]

Appl Environ Microbiol, 2019
Jiang X, Geng Y, Ren S, Yu T, Li Y, Liu G, Wang H, Meng H, Shi L.   +8 more
europepmc   +1 more source

Safe and Efficient CRISPR Genome Editing of Primary Human T Cells Using a Droplet‐Based Cell Mechanoporation Platform

Small, Volume 22, Issue 19, 1 April 2026.
This study introduces a microfluidic droplet mechanoporation system for the engineering of primary human T cells. The platform enables efficient, scalable, and robust delivery of mRNA for CAR T cell production and CRISPR‐Cas9 ribonucleoproteins for genome editing, while maintaining high cell viability.
You‐Jeong Kim, Sungwon Bang, Aram J. Chung   +2 more
wiley   +1 more source