Results 141 to 150 of about 241,979 (317)

Lupeol as a Potential Inhibitor of NorA Efflux Pumps in Staphylococcus aureus: In Silico and In Vitro Evidence

open access: yesChemistryOpen, EarlyView.
Antimicrobial resistance remains one of the major challenges to global public health, compromising the effectiveness of treatments and contributing to increased morbidity and mortality associated with bacterial infections. Among the mechanisms involved, efflux pumps—such as NorA, expressed in resistant strains of Staphylococcus aureus—are particularly ...
Nara Juliana Santos Araújo   +15 more
wiley   +1 more source

The influence of flavin mononucleotide on interaction in ethidium bromide-DNA system

open access: yesБіофізичний вісник, 2015
The study of intercalator ethidium bromide (EB) interaction with DNA in the presence of vitamin B2 analogue flavin mononucleotide (FMN) is carried out using the differential scanning calorimetry (DSC) and spectrophotometry (SF).
А. А. Герус   +6 more
doaj  

Synergistic Effect of Prolonged Oxygenation and Reactive Oxygen Species Scavenging on Diabetic Wound Healing Using an Injectable Thermoresponsive Hydrogel

open access: yesSmall, EarlyView.
The oxygen‐generating and reactive oxygen species‐scavenging hydrogel (ORH) exhibits thermoresponsive gelation and incorporates oxygen‐generating microspheres(OGMs) and chitosan‐catalase complexes(CSCATs) via hydrophobic and ionic interactions. Upon injection into irregular wound sites, ORH forms a gel at body temperature and sustains the release of ...
Jiyeon Lee   +3 more
wiley   +1 more source

Bicontinuous Interconnected Porous Biomaterials for Tissue Engineering and Regeneration

open access: yesSmall Science, EarlyView.
Solvent transfer‐induced phase separation transforms bioinert polyethylene glycol diacrylate into bioactive scaffolds featuring bicontinuous interconnected porosity, with negative Gaussian curvature, and unique topographical patterning. These attributes enable stem cell attachment, proliferation, and differentiation without basement membrane matrix ...
Aihik Banerjee   +16 more
wiley   +1 more source

Cationic Polyelectrolyte Adsorption onto Anionic Nanoparticles Analyzed with Frequency‐Domain Scanning Fluorescence Correlation Spectroscopy

open access: yesSmall Methods, EarlyView.
A small‐circle scanning fluorescence correlation spectroscopy (sFCS) technique is presented using acousto‐optical laser scanning and frequency‐domain fitting. Validated with simulations and experiments, sFCS investigates cationic polyelectrolyte adsorption onto anionic nanoparticles, revealing stable complexes and size increases with polymer mass ...
Lucas Oorlynck   +9 more
wiley   +1 more source

Comprehensive Osteosarcoma Treatment with Multifunctional Composite Hydrogels Enabling Combined Photothermal Cancer Ablation and Osteoinductive Tissue Regeneration

open access: yesSmall Methods, EarlyView.
This study presents a comprehensive strategy for treating osteosarcoma and promoting bone tissue regeneration using a multifunctional composite hydrogel composed of mineralized fibers with polyphenols. Furthermore, the biomaterial effectively mitigates the degenerative microenvironment including oxidative stress that develops after tumor ablation. This
Hayeon Byun   +8 more
wiley   +1 more source

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