Results 141 to 150 of about 246,567 (336)

Extracting physical chemistry from mechanics: a new approach to investigate DNA interactions with drugs and proteins in single molecule experiments

open access: yes, 2015
In this review we focus on the idea of establishing connections between the mechanical properties of DNAligand complexes and the physical chemistry of DNA-ligand interactions.
Rocha, M. S.
core   +1 more source

USP44, ZNF454, and GPRC5B ctDNA Methylation Markers in Breast Cancer: Limited Clinical Relevance for Disease Monitoring and Tumor Characteristics

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
We selected breast cancer‐specific DNA methylation markers using The Cancer Genome Atlas (TCGA). We analyzed the methylation and expression patterns of candidate genes in breast cancer cell lines, ctDNA, and tissue samples. The relationship between ctDNA methylation markers and the clinicopathological features of breast cancer patients was investigated.
Young Ju Jeong   +6 more
wiley   +1 more source

Toxoplasma gondii attenuates the Ethidium bromide induced demyelination lesions in multiple sclerosis model rats [PDF]

open access: green, 2022
Seyedmousa Motavallihaghi   +4 more
openalex   +1 more source

TbTim20 facilitates protein import at a low membrane potential in trypanosomes lacking the mitochondrial genome

open access: yesThe FEBS Journal, EarlyView.
Protein import into mitochondria relies on TIM complexes and the membrane potential. Trypanosoma brucei has a unique TIM complex, and the role of one subunit, TbTim20, has remained unclear. Here, we show that TbTim20 is essential in cells lacking mitochondrial DNA. The importance of TbTim20 increases as the membrane potential decreases.
Corinne von Känel   +8 more
wiley   +1 more source

The influence of flavin mononucleotide on interaction in ethidium bromide-DNA system

open access: yesБіофізичний вісник, 2015
The study of intercalator ethidium bromide (EB) interaction with DNA in the presence of vitamin B2 analogue flavin mononucleotide (FMN) is carried out using the differential scanning calorimetry (DSC) and spectrophotometry (SF).
А. А. Герус   +6 more
doaj  

EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier

open access: yesThe FEBS Journal, EarlyView.
Cell‐surface CLDN‐5 protein levels can be evaluated using a probe that can bind to the extracellular domains of CLDN‐5. A probe derived from Clostridium perfringens enterotoxin allows us to isolate cells with high CLDN‐5 protein levels from a knockout cell library.
Yosuke Hashimoto   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy