Results 11 to 20 of about 11,595 (100)

Decreased Production of Tissue Plasminogen Activator in Endothelial Cells From Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Previous studies have demonstrated that chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by excessive fibrin deposition which is related to impaired production of tissue plasminogen activator(t‐PA) by epithelial cells.
Qian‐Qian Zhang, Chen Zhang, Jia‐Ni Chen, Fu‐Ying Cheng, Yi‐Zhang Wang, Shi‐Rui Xue, Huan Wang, De‐Hui Wang, Xi‐Cai Sun, Li Hu   +9 more
wiley   +1 more source

Morphological Sinus Features and Chronic Rhinosinusitis Risk: A Radiomics Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Anatomical factors of the sinuses significantly impact the progression of chronic rhinosinusitis (CRS). This study aims to investigate the correlation between morphological sinus features and the risk of CRS onset to provide evidence‐based support for clinical management.
Song Luo, Xiang‐Hai Hu, Min Yin, Song Li, Lei Cheng   +4 more
wiley   +1 more source

Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000–2018)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high‐power field, requiring accuracy optimization.
Ning Kang, Man‐Hou Chao, Xin Luo, Feng‐Wen Shan, Zi‐Xuan Hua, Ze‐Zhi Guo, Hua‐Mei Yan, He Zhang, Tong Wu, Min Zhou, Rui Zheng, Shuo Wu, Xue‐Kun Huang, Zhao‐Hui Shi, Ya‐Na Zhang, Ji Yang, Qin‐Tai Yang   +16 more
wiley   +1 more source

Prelacrimal Transmaxillary‐Orbital Approach for Resection of Lateral Extraconal Orbital Cavernous Hemangioma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Endoscopic orbital surgery is likely a reasonable option for patients with orbital cavernous hemangiomas (OCH) medial to the optic nerve (ON). The endoscopic resection of OCH lateral to the ON is extremely challenging. Zhou et al. first described the endoscopic prelacrimal recess approach (PLRA) for the management of the maxillary sinus and ...
Zhen‐Xiao Huang, Xiao‐Qing Zhang, Bing Zhou   +2 more
wiley   +1 more source

“Super‐Responders” to Dupilumab Treatment in Patients With Primary Diffuse Chronic Rhinosinusitis With Nasal Polyps

Allergy, EarlyView.
This study aimed to evaluate the feasibility of extending dupilumab dosing intervals in T2‐CRSwNP by assessing how many patients maintain disease control with once‐every‐12‐weeks (Q12W) dosing and comparing clinical characteristics of super‐responders and excellent responders. Tapering of dupilumab to Q12W appears feasible in super‐responding patients.
P. E. Vonk, J. J. Otten, H. B. E. Elzinga, R. J. L. van der Lans, G. F. J. P. Adriaensen, L. B. L. Benoist, D. R. Hoven, W. J. Fokkens, S. Reitsma, PolyREG Consortium, A.B. Rinia, I. Krebbers, I.J. Kleiss, M. E. Cornet   +13 more
wiley   +1 more source

IL‐33 Drives Inflammatory Changes and Extracellular Trap Formation in Eosinophils Involving Oxidised LDL and Complement Pathways

Allergy, EarlyView.
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama, Jun Miyata, Takao Mochimaru, Ryuta Onozato, Yo Otsu, Hisashi Sasaki, Keeya Sunata, Shinichi Okuzumi, Katsunori Masaki, Hiroki Kabata, Keinosuke Hizuka, Yoshinori Hasegawa, Ryo Konno, Yusuke Kawashima, Makoto Arita, Shigeharu Ueki, Koichi Fukunaga   +16 more
wiley   +1 more source

Association of Maxillofacial Fractures With Demographic and Dental Factors: The Roles of Edentulism, Posterior Occlusion, Canines, and Lower Third Molar

Dental Traumatology, EarlyView.
ABSTRACT Background/Aim This retrospective, two‐center study aims to improve understanding of fracture pathogenesis in maxillofacial trauma by examining variations related to sex, age, dental status, posterior occlusion, and the presence of lower third molars (LTM) and lower canines.
Canan Uzun, Ceyhun Uzun, Savas Ozarslanturk, Emrah Kagan Yasar   +3 more
wiley   +1 more source

Rhinoscopy in horses: Endoscopic anatomy, technique and equipment

Equine Veterinary Education, EarlyView.
Summary Rhinoscopy is a valuable imaging modality for diagnosis of conditions affecting the nasal and paranasal cavities in horses. Despite wide application in clinical practice, systematic endoscopic evaluation of the conchal bullae, nasal conchae and adjacent structures has seldom been described.
J. W. C. Lopes, R. P. Mendes, S. L. Paredes, K. A. G. Vallejo, P. S. Rocha, R. G. S. Dória, R. R. Corrêa   +6 more
wiley   +1 more source

Long‐term stability of transcrestal sinus augmentation

Periodontology 2000, EarlyView.
Abstract Transcrestal sinus augmentation has emerged as a minimally invasive alternative to lateral window techniques for vertical bone augmentation in the edentulous maxilla. Since its early introduction and modification over the last several decades, this technique has demonstrated predictable outcomes for implant placement in regions with limited ...
Sandra H. Stuhr, Muhammad H. A. Saleh, Tiziano Testori, Hom‐Lay Wang, Ann M. Decker   +4 more
wiley   +1 more source

Long‐term stability of sinus complication management

Periodontology 2000, EarlyView.
Abstract Maxillary sinus augmentation shows a low incidence of complications and high clinical success due to favorable biological conditions and typically transient issues. Most complications are intraoperative, such as Schneiderian membrane perforation or hemorrhage, and are often resolved immediately.
Pablo Galindo‐Moreno, Tiziano Testori, Miguel Padial‐Molina, Allinson Olaechea, Francisco O'Valle, Pablo Galindo‐Fernandez   +5 more
wiley   +1 more source