Results 131 to 140 of about 13,235,717 (359)

Racial and Ethnic Groups [PDF]

, 1989
Willie Melton, Richard T.Schaefer
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Trends in hepatocellular carcinoma stage by racial/ethnic group in the United States, 1992-2019. [PDF]

JHEP Rep, 2023
Alvarez CS, Ruhl J, Flynn G, Graubard BI, McGlynn KA.   +4 more
europepmc   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Cultural Contrasts and Similarities Among Five Ethnic Groups in the Nilgiri District, Madras State, India, 1800-1963.

, 1968
W. J. Le Noble
openalex   +2 more sources

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Wild edible plants and their cultural significance among the Zhuang ethnic group in Fangchenggang, Guangxi, China. [PDF]

J Ethnobiol Ethnomed, 2023
Liu S, Huang X, Bin Z, Yu B, Lu Z, Hu R, Long C.   +6 more
europepmc   +1 more source

Vitamin A reserve of liver in health and coronary heart disease among ethnic groups in Singapore [PDF]

, 1988
N. Saha, Thian-C Ng, Puay Yok Tan, K. P. Wee   +3 more
openalex   +1 more source

Do dimensions of ethnic identity mediate the association between perceived ethnic group discrimination and depressive symptoms?

Cultural diversity & ethnic minority psychology, 2015
Aerika S. Brittian, Su Yeong Kim, Brian E Armenta, Richard M. Lee, A. Umaña‐Taylor, S. Schwartz, Ian K. Villalta, Byron L. Zamboanga, Robert S. Weisskirch, Linda P. Juang, Linda G. Castillo, M. Hudson   +11 more
semanticscholar   +1 more source