Results 151 to 160 of about 503,750 (307)

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Influence of ethnicity on plantar loading of the paediatric foot: an exploratory analysis

Journal of Foot and Ankle Research, 2015
Stewart C Morrison, Stephen Cousins, Charlotte Vannet, Wendy Drechsler   +3 more
doaj   +1 more source

Knowledge Architecture for Race and Ethnic Group Defining in Learning Health Systems. [PDF]

Learn Health Syst
Hudson MF, van Staden VMS, Oostdyk AM, Martin JC.   +3 more
europepmc   +1 more source

Trends in hepatocellular carcinoma stage by racial/ethnic group in the United States, 1992-2019. [PDF]

JHEP Rep, 2023
Alvarez CS, Ruhl J, Flynn G, Graubard BI, McGlynn KA.   +4 more
europepmc   +1 more source

The cultural ecology of trust – Melbourne’s ethnic-based money transfer operators struggle for recognition

, 2015
Estimates show that 6.5 million Australians with family or friends overseas rely on money transfer services.  From 2013 to 2015 the major Australian banks closed their remittance accounts with a devastating effect on Victorian communities with ...
Ethnic Communities' Council of Victoria
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Population Genetic Data for 23 STR Loci of the Black Caribbean Ethnic Group in Honduras. [PDF]

Genes (Basel)
Zuniga A, Molina Y, Amaya K, Moya Z, Soriano P, Pineda D, Pinto Y, Garcia O, Zablah I.   +8 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Population Genetic Data for 23 STR Loci of the Pech Ethnic Group in Honduras. [PDF]

Genes (Basel)
Zuniga A, Molina Y, Amaya K, Moya Z, Soriano P, Pineda D, Pinto Y, García O, Zablah I.   +8 more
europepmc   +1 more source

Oral health of an indigenous population in northeastern Brazil: a cross-sectional Study of the Fulni-ô ethnic group. [PDF]

Sao Paulo Med J, 2023
Koike BDV, Valões RMP, Cazal C, Pereira VC, Fraga CAC, Carmo RFD, Pereira MF, Guimarães MP, Souza CDF, Armstrong ADC.   +9 more
europepmc   +1 more source