Results 151 to 160 of about 6,177,093 (289)

Influence of Pre-treatment CA 125 Levels on Survival Outcomes Across Ethnic Groups in Ovarian Cancer Patients. [PDF]

J Community Hosp Intern Med Perspect
Bangolo A, Amoozgar B, Zhang L, Alqinai B, Hodzic L, Nadella P, Patel M, Roy K, Lakshmana V, Sharma N, Sultana S, Yohannes B, Tran HH, Ingersoll G, Thet PM, Senevirathne RW, Chandak P, Maharaj N, Aloimonos C, Safdar M, Priyabhashinie C, Samuel B, Bommepalli M, Tun Y, Swarath S, Kumar N, Goyal R, Salih SA, Wiredu IO, Umanets E, Kiadidi LL, Dhakal P, Kaur T, Du D, Gill K, Khan MAR, Arteaga C, Barbosa H, Weissman S.   +38 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Carotid Atherosclerosis and Metabolic Characteristics Among High-Risk Cardiovascular Populations of Four Ethnic Groups - Yunnan Province, China, 2024. [PDF]

China CDC Wkly
Yan W, Wen H, Fu H, Chen B, Song A, Wen W, Chen Y.   +6 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

The Variation in IRT in Different Ethnic Groups in England-Implications for a Newborn Screening Programme for CF in Diverse Multiethnic Populations. [PDF]

Int J Neonatal Screen
Greenfield T, Tetlow L, Bonham JR, Collingwood C, Wainwright L, Robinson L, Wright D, Hird B, Ramgoolam T, Griffith C, Shakespeare L, Mirzazadeh M, Garstone R, Finnerty D, Flynn N, Taj N, Desai M.   +16 more
europepmc   +1 more source

Ethnic Group [PDF]

, 2020
openaire   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Genetic polymorphisms in cardiovascular disease susceptibility among different ethnic groups. [PDF]

Bioinformation
Chauhan P, Jha H, Podder A.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source