Results 191 to 200 of about 6,446,544 (290)

Distributions of Adverse Childbearing Experiences Across Racial and Ethnic Groups: A Research Note. [PDF]

Demography
Thomeer MB, Williams C.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

PRANA: A Deep Learning Method for Adapting Polygenic Risk Scores to Diverse Ethnic Groups

Levi H, Wang Q, Bolla MK, Dennis J, Andrulis IL, Antonenkova N, Au CH, Augustinsson A, Freeman LEB, Behrens S, Bermisheva M, Bodelon C, Bogdanova NV, Bojesen SE, Brenner H, Brock IW, Brüning T, Byers H, Camp NJ, Castelao JE, Choi J, Chung WK, NBCS Collaborators, Colonna SV, Couch FJ, Czene K, Daly MB, Devilee P, Dörk T, Eliassen AH, Eriksson M, Evans DG, Fasching PA, Faw K, Gago-Dominguez M, García-Closas M, Haiman CA, Hamann U, Hartman M, Ho V, Ho PJ, Hooning MJ, Hoppe R, Howell SJ, ABCTB Investigators, SGBCC Investigators, Ito H, Iwasaki M, Jakubowska A, Jernström H, Joseph V, Kaaks R, Kang D, Khusnutdinova EK, Kiprijanovska S, Koutros S, Kristensen VN, Kurian AW, Kwong A, Lambrechts D, Larson NL, Marchand LL, Li S, Li J, Lophatananon A, Mannermaa A, Matsuo K, Maxwell W, Muir K, Nevelsteen I, Obi N, O’Brien KM, Ofit K, Ottewell PD, Patel AV, Peterlongo P, Plaseska-Karanfilska D, Prajzendanc K, Radice P, Ramachandran D, Rashid MU, Romero A, Saloustros E, Sandler DP, Schöttker B, Simard J, Southey MC, Stone J, Sugier P, Taylor JA, Teras LR, Truong T, Weinberg CR, Yadav S, Yamaji T, Zheng W, Dunning AM, Mavaddat N, Easton DF, Michailidou K, Elkon R, Shamir R.   +101 more
europepmc   +1 more source

Trends in Early-Onset Colorectal Adenocarcinoma and Neuroendocrine Tumors Across Racial and Ethnic Groups. [PDF]

J Clin Med
Patel C, Abboud Y, Karkra R, Qureshi I, Gaglio P, Lingiah V, Al-Khazraji A, Hajifathalian K.   +7 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Trends in opioid prescribing after shoulder arthroplasty in an integrated health system: an analysis across racial and ethnic groups. [PDF]

J Shoulder Elb Arthroplast
Alfaro DO, Zhuang Z, Davis A, Prentice HA, Schmidt AM, Navarro RA.   +5 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Weight stigma among diverse ethnic groups with obesity in the U.S.: the USA-OBESTIGMA study. [PDF]

Int J Obes (Lond)
Galindo RJ, Arevalo G, Zabala Z, Flores I, Soliman D, Moazzami B, Rashied A, Lecube A, Umpierrez GE.   +8 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Inequalities in Childhood Healthcare Access Among Racial and Ethnic Groups of Sub-Saharan Africa: A Narrative Review. [PDF]

Children (Basel)
Azhar SH, Sárváry A, Sárváry A.
europepmc   +1 more source