Results 181 to 190 of about 6,177,093 (289)

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Inequalities in Childhood Healthcare Access Among Racial and Ethnic Groups of Sub-Saharan Africa: A Narrative Review. [PDF]

Children (Basel)
Azhar SH, Sárváry A, Sárváry A.
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Weight stigma among diverse ethnic groups with obesity in the U.S.: the USA-OBESTIGMA study. [PDF]

Int J Obes (Lond)
Galindo RJ, Arevalo G, Zabala Z, Flores I, Soliman D, Moazzami B, Rashied A, Lecube A, Umpierrez GE.   +8 more
europepmc   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

PRANA: A Deep Learning Method for Adapting Polygenic Risk Scores to Diverse Ethnic Groups

Levi H, Wang Q, Bolla MK, Dennis J, Andrulis IL, Antonenkova N, Au CH, Augustinsson A, Freeman LEB, Behrens S, Bermisheva M, Bodelon C, Bogdanova NV, Bojesen SE, Brenner H, Brock IW, Brüning T, Byers H, Camp NJ, Castelao JE, Choi J, Chung WK, NBCS Collaborators, Colonna SV, Couch FJ, Czene K, Daly MB, Devilee P, Dörk T, Eliassen AH, Eriksson M, Evans DG, Fasching PA, Faw K, Gago-Dominguez M, García-Closas M, Haiman CA, Hamann U, Hartman M, Ho V, Ho PJ, Hooning MJ, Hoppe R, Howell SJ, ABCTB Investigators, SGBCC Investigators, Ito H, Iwasaki M, Jakubowska A, Jernström H, Joseph V, Kaaks R, Kang D, Khusnutdinova EK, Kiprijanovska S, Koutros S, Kristensen VN, Kurian AW, Kwong A, Lambrechts D, Larson NL, Marchand LL, Li S, Li J, Lophatananon A, Mannermaa A, Matsuo K, Maxwell W, Muir K, Nevelsteen I, Obi N, O’Brien KM, Ofit K, Ottewell PD, Patel AV, Peterlongo P, Plaseska-Karanfilska D, Prajzendanc K, Radice P, Ramachandran D, Rashid MU, Romero A, Saloustros E, Sandler DP, Schöttker B, Simard J, Southey MC, Stone J, Sugier P, Taylor JA, Teras LR, Truong T, Weinberg CR, Yadav S, Yamaji T, Zheng W, Dunning AM, Mavaddat N, Easton DF, Michailidou K, Elkon R, Shamir R.   +101 more
europepmc   +1 more source

Understanding Social Drivers of Health, Burden, and Impact of Hidradenitis Suppurativa among Different Racial and Ethnic Groups in the USA. [PDF]

Dermatol Ther (Heidelb)
Jaleel T, Chovatiya R, Bacci ED, Pierce E, Constantine ML, Correll JR, Mitchell B, Patel DR, Brooks B, Heath C, Shi VY.   +10 more
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Trends in unawareness of cardiovascular disease risk factors among racial & ethnic groups in the United States. [PDF]

Am J Prev Cardiol
Ibrahim R, Awad K, Hafez A, Pham HN, Tan MC, Salih M, Lee JZ, Sorajja D, Scott LR, Ayoub C, Arsanjani R.   +10 more
europepmc   +1 more source