Results 41 to 50 of about 15,081,734 (309)

Ethnic differences in the prevalence of frailty in the United Kingdom assessed using the electronic Frailty Index

open access: yesAging Medicine, 2019
Objective There have been few studies in which the prevalence of frailty of different ethnic groups has been assessed in multiethnic countries. The aim of this study was to evaluate the prevalence of frailty in different ethnic groups in the United ...
Shraddha Pradhananga   +5 more
doaj   +1 more source

Population genomics of East Asian ethnic groups

open access: yesHereditas, 2020
East Asia constitutes one-fifth of the global population and exhibits substantial genetic diversity. However, genetic investigations on populations in this region have been largely under-represented compared with European populations.
Ziqing Pan, Shuhua Xu
doaj   +1 more source

Prevalence of Malocclusion in Brazilian Quilombola Adolescents

open access: yesDentistry 3000, 2022
Objective: To evaluate the prevalence of malocclusion in Quilombola adolescents living in rural area in Northeastern Brazil. Material and Methods: This is a cross-sectional study in which 36 Quilombola adolescents aged 12-19 years were evaluated.
Gabrielli Oliveira de Brito   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

The social origin of the illness experience – an outline of problems

open access: yesAnnals of Agricultural and Environmental Medicine, 2014
[b]Introduction and objective[/b]. The main research objective is a study of social influences on the processes of experiencing illness in the sociological meaning of the term ‘illness experience’ focusing attention on the subjective activity inspired by
Michał Skrzypek
doaj  

Induction effect of exogenous arachidonic acid on resistance to white leaf spot in maize

open access: yesBMC Plant Biology
Background White leaf spot in maize (WLS) severely threatens maize yield and quality. Risk assessment suggests that it may become one of the most significant maize diseases in China.
Ru Xia   +15 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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