Results 71 to 80 of about 9,665,153 (294)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
New Jersey Multi-Ethnic Oral History Project Interview with Ms. Ila Shah
This interview was conducted as part of the New Jersey Historical Commission Grant-funded Multi-Ethnic Oral History Project. The interviewee is Mrs. Ila Shah. Mrs. Shah came to the United States in 1972 with her husband, who is a physician. Mrs.
core +1 more source
Ethnic Studies Newsletter Vol. 8 No. 1
Six page newsletter from the Ethnic Studies department dated November 1989. Newsletter is Volume 8, Number 1. Newsletter includes Feature recognizing the following three faculty members who joined Ethnic Studies since the last newsletter: Dr.
Ethnic Studies Department;
core +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
New Jersey Multi-Ethnic Oral History Project Interview with Antoinette Bjorklund
Interview conducted by Carol Ann Raines for the New Jersey Historical Commission's New Jersey Multi-Ethnic Oral History Project. The interview is with Antoinette Bjorklund who was born in Philadelphia, Pennsylvania, and whose parents immigrated to the ...
core +1 more source
History of the Discussion on Ethnic Difference at ICH
This paper describes the history of discussions on ethnic differences at the International Conference on Harmonization of technical requirements for registration of pharmaceuticals for human use (ICH). The first part of this paper gives a short outline of the purpose, organization, history, decision making process of the ICH.
openaire +3 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
New Jersey Multi-Ethnic Oral History Project Interview with Ms. Sharda Shenoy, Indian-American
This interview was conducted as part of the New Jersey Historical Commission Grant-funded Multi-Ethnic Oral History Project. The interviewee is Ms. Shard Shenoy. Ms. Shenoy talks about founding her business, Elegant Affairs, with her sister, Ms. Shobha
core +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source

